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Prognosis factors of survival in patients with liver cirrhosis and portal hypertension.
Olevskaya, E R; Dolgushina, A I; Tarasov, A N; Hihlova, A O.
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  • Olevskaya ER; South Ural State Medical University of the Ministry of Health of the Russian Federation, Chelyabinsk, Russia.
  • Dolgushina AI; South Ural State Medical University of the Ministry of Health of the Russian Federation, Chelyabinsk, Russia.
  • Tarasov AN; South Ural State Medical University of the Ministry of Health of the Russian Federation, Chelyabinsk, Russia.
  • Hihlova AO; South Ural State Medical University of the Ministry of Health of the Russian Federation, Chelyabinsk, Russia.
Ter Arkh ; 91(2): 67-72, 2019 Mar 18.
Article en En | MEDLINE | ID: mdl-31094174
AIM: To study prognostic factors for survival in patients of liver cirrhosis (LC) with portal hypertension (PG). MATERIALS AND METHODS: 155 patients (women - 49.4%, men - 50.6%, median age 56.4 years [51.3; 61.6]) were follow up for 36 months. Viral LC was diagnosed in 33.8%, alcohol LC - 22.1%, autoimmune LC - 15.6%, other causes and cryptogenic causes noted in - 28.5%. More than half of the patients had a class В of Child-Pugh (51.9%). RESULTS: During the study period 42 patients (28.3%) died. The analysis of survival by various factors for Kaplan-Mayer was carried out. Significant predictors: Child-Pugh class, LC etiology, comorbidity in Charlson scores, adherence to endoscopic treatment of esophageal varices were included in the model of proportional Cox risks. In a single-factor analysis, the risk of death is higher in patients who violate the timing of endoscopic treatment, but this factor has lost significance in the multifactor model. Patient with Child-Pugh C, alcoholic LC, comorbidity more 5 points by Charlson score have a higher mortality risk. CONCLUSION: Identification of risk factors that affect the survival of LC patients will allow to use of an individual plan for the LC treatment and prevention of PG complications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipertensión Portal / Cirrosis Hepática Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Ter Arkh Año: 2019 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipertensión Portal / Cirrosis Hepática Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Ter Arkh Año: 2019 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia