Phosphorylation of Hsp20 Promotes Fibrotic Remodeling and Heart Failure.

Gardner, George T; Travers, Joshua G; Qian, Jiang; Liu, Guan-Sheng; Haghighi, Kobra; Robbins, Nathan; Jiang, Min; Li, Yutian; Fan, Guo-Chang; Rubinstein, Jack; Blaxall, Burns C; Kranias, Evangelia G

Gardner, George T; Travers, Joshua G; Qian, Jiang; Liu, Guan-Sheng; Haghighi, Kobra; Robbins, Nathan; Jiang, Min; Li, Yutian; Fan, Guo-Chang; Rubinstein, Jack; Blaxall, Burns C; Kranias, Evangelia G.

Afiliación

Gardner GT; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Travers JG; Department of Pediatrics, Division of Molecular Cardiovascular Biology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Qian J; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Liu GS; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Haghighi K; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Robbins N; Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Jiang M; Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Li Y; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Fan GC; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Rubinstein J; Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Blaxall BC; Department of Pediatrics, Division of Molecular Cardiovascular Biology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Kranias EG; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

JACC Basic Transl Sci ; 4(2): 188-199, 2019 Apr.

Article en En | MEDLINE | ID: mdl-31061921

Palabras clave

Ccl2, C-C motif chemokine ligand 2; Ccl3, C-C motif chemokine ligand 3; Col1a1, collagen 1A1; Col3A1, collagen 3A1; ECM, extra-cellular matrix; Hsp, heat shock protein; Hsp20; I/R, ischemia/reperfusion; IL, interleukin; IL-6; Postn, periostin; SMA, smooth muscle actin; STAT3, signal transducer and activator of transcription 3; TG, transgenic; TGF, transforming growth factor; TNF, tumor necrosis factor; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling; WT, wild type; fibroblast; heart failure; remodeling

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Basic Transl Sci Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

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