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Revisiting total recognition discriminability in Huntington's and Alzheimer's disease: New insights from the CVLT-3.
Graves, Lisa V; Simone, Stephanie; Williams, McKenna; Courville, Troy; Mattson, Sarah N; Delano-Wood, Lisa; Bondi, Mark W; Salmon, David P; Corey-Bloom, Jody; Delis, Dean C; Gilbert, Paul E.
Afiliación
  • Graves LV; San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
  • Simone S; Department of Psychology, San Diego State University, San Diego, California, USA.
  • Williams M; Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, California, USA.
  • Courville T; Department of Psychology, San Diego State University, San Diego, California, USA.
  • Mattson SN; Professional Education, Georgia Institute of Technology, Atlanta, Georgia, USA.
  • Delano-Wood L; San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
  • Bondi MW; Department of Psychology, San Diego State University, San Diego, California, USA.
  • Salmon DP; San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
  • Corey-Bloom J; Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, California, USA.
  • Delis DC; Veterans Affairs San Diego Healthcare System, San Diego, California, USA.
  • Gilbert PE; San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
Appl Neuropsychol Adult ; 28(2): 132-139, 2021.
Article en En | MEDLINE | ID: mdl-31060389
The original and second editions of the California Verbal Learning Test (CVLT) used nonparametric and parametric methods, respectively, to assess Total Recognition Discriminability (RD). In a previous study, we found evidence that the nonparametric formula may be more sensitive than the parametric formula to high false positive (FP) rates and provide more accurate assessments of yes/no recognition in neurodegenerative populations prone to high FP rates, including Alzheimer's disease (AD). In the present study, we extended our investigation to examine the utility of CVLT-3 nonparametric and parametric Total RD indices in the assessment and comparison of yes/no recognition in individuals with Huntington's disease (HD) and AD in mild and moderate stages of dementia. Findings suggested that the CVLT-3 nonparametric Total RD index was more sensitive than the parametric index to HD and AD differences in yes/no recognition across mild and moderate stages of dementia. Additionally, group differences on total FP errors were more closely mirrored by group differences on the nonparametric Total RD index. The present results bolster our previous findings and highlight the utility of examining nonparametric (in addition to parametric) Total RD on the CVLT-3 in assessments of yes/no recognition involving clinical populations prone to high FP rates.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Enfermedad de Alzheimer Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Appl Neuropsychol Adult Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Enfermedad de Alzheimer Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Appl Neuropsychol Adult Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos