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The Turkish experience with therapeutic plasma exchange: A national survey.
Korkmaz, Serdal; Solmaz Medeni, Serife; Demirkan, Fatih; Kalayoglu Besisik, Sevgi; Altay Dadin, Senem; Akgun Cagliyan, Gulsum; Kabukcu Hacioglu, Sibel; Sari, Ismail; Goren Sahin, Deniz; Arat, Mutlu; Dagdas, Simten; Ozet, Gulsum; Kutlu, Nermin; Karaagac Akyol, Tulay; Ozcebe, Osman Ilhami; Uskudar Teke, Hava; Kiper Unal, Demet; Guner, Naile; Tombak, Anil; Celik, Halil; Bay, Ilker; Kiki, Ilhami; Ozgur, Gokhan; Erkurt, Mehmet Ali; Ozatli, Duzgun; Meletli, Ozgur; Demircioglu, Sinan; Demir, Cengiz; Kurtoglu, Erdal; Vural, Filiz; Tobu, Mahmut; Karakus, Abdullah; Ayyildiz, Orhan; Dal, Mehmet Sinan; Afacan Ozturk, Berna; Albayrak, Murat; Ocakci, Serkan; Bolaman, Zahit; Sonmez, Mehmet; Karakus, Volkan; Gokmen Sevindik, Omur; Berber, Ilhami; Dogu, Mehmet Hilmi; Gulturk, Emine; Ulas, Turgay; Payzin, Bahriye; Kuku, Irfan; Cagirgan, Seckin; Altuntas, Fevzi.
Afiliación
  • Korkmaz S; University of Health Sciences, Kayseri Training and Research Hospital, Department of Hematology, Kayseri, Turkey. Electronic address: baranserdalkorkmaz@gmail.com.
  • Solmaz Medeni S; University of Health Sciences, Bozyaka Training and Research Hospital, Department of Hematology, Izmir, Turkey.
  • Demirkan F; Dokuz Eylul University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, HCT Unit, Izmir, Turkey.
  • Kalayoglu Besisik S; Istanbul University, Istanbul Medical Faculty, Department of Internal Medicine, Division of Hematology, Istanbul, Turkey.
  • Altay Dadin S; Istanbul University, Istanbul Medical Faculty, Department of Internal Medicine, Division of Hematology, Istanbul, Turkey.
  • Akgun Cagliyan G; Pamukkale University, Department of Internal Medicine, Division of Hematology, Denizli, Turkey.
  • Kabukcu Hacioglu S; Pamukkale University, Department of Internal Medicine, Division of Hematology, Denizli, Turkey.
  • Sari I; Pamukkale University, Department of Internal Medicine, Division of Hematology, Denizli, Turkey.
  • Goren Sahin D; Istanbul Bilim University Medical School, Department of Hematology, Istanbul, Turkey; Sisli Florence Nightingale Hospital, Stem Cell Transplantation Unit, Istanbul, Turkey.
  • Arat M; Sisli Florence Nightingale Hospital, Stem Cell Transplantation Unit, Istanbul, Turkey.
  • Dagdas S; Ankara Numune Training and Research Hospital, Department of Hematology, Ankara, Turkey.
  • Ozet G; Ankara Numune Training and Research Hospital, Department of Hematology, Ankara, Turkey.
  • Kutlu N; Hacettepe University, School of Medicine, Therapeutic Apheresis Unit, Ankara, Turkey.
  • Karaagac Akyol T; Hacettepe University, School of Medicine, Therapeutic Apheresis Unit, Ankara, Turkey.
  • Ozcebe OI; Hacettepe University, School of Medicine, Department of Hematology, Ankara, Turkey.
  • Uskudar Teke H; Eskisehir Osmangazi University, School of Medicine, Department of Internal Medicine, Division of Hematology, Eskisehir, Turkey.
  • Kiper Unal D; Izmir Katip Celebi University, Ataturk Training and Research Hospital, Department of Hematology, Izmir, Turkey.
  • Guner N; Izmir Katip Celebi University, Ataturk Training and Research Hospital, Department of Hematology, Izmir, Turkey.
  • Tombak A; Mersin University, Faculty of Medicine, Department of Internal Medicine, Division of Heamatology, Mersin, Turkey.
  • Celik H; Mersin University, Faculty of Medicine, Department of Internal Medicine, Mersin, Turkey.
  • Bay I; Ataturk University, School of Medicine, Department of Internal Medicine, Division of Hematology, Erzurum, Turkey.
  • Kiki I; Ataturk University, School of Medicine, Department of Internal Medicine, Division of Hematology, Erzurum, Turkey.
  • Ozgur G; Gulhane Training and Research Hospital, Hematology and HCT Clinic, Ankara, Turkey.
  • Erkurt MA; Inonu University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Malatya, Turkey.
  • Ozatli D; Ondokuz Mayis University, Faculty of Medicine, Department of Hematology, Samsun, Turkey.
  • Meletli O; Ondokuz Mayis University, Faculty of Medicine, Department of Hematology, Samsun, Turkey.
  • Demircioglu S; Yüzüncü Yil University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Van, Turkey.
  • Demir C; Yüzüncü Yil University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Van, Turkey.
  • Kurtoglu E; University of Health Sciences, Antalya Training and Research Hospital, Department of Hematology, Antalya, Turkey.
  • Vural F; Ege University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Izmir, Turkey.
  • Tobu M; Ege University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Izmir, Turkey.
  • Karakus A; Dicle University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Diyarbakir, Turkey.
  • Ayyildiz O; Dicle University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Diyarbakir, Turkey.
  • Dal MS; University of Health Sciences, Ankara Oncology Training and Research Hospital, Department of Hematology and BMT Unit, Ankara, Turkey.
  • Afacan Ozturk B; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Hematology and HCT Clinic, Ankara, Turkey.
  • Albayrak M; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Hematology and HCT Clinic, Ankara, Turkey.
  • Ocakci S; Medical Park Izmir Hospital, Department of Hematology, Izmir, Turkey.
  • Bolaman Z; Adnan Menderes University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Aydin, Turkey.
  • Sonmez M; Karadeniz Technical University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Trabzon, Turkey.
  • Karakus V; Mugla Sitki Kocman University Training and Research Hospital, Department of Hematology, Mugla, Turkey.
  • Gokmen Sevindik O; Firat University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Elazig, Turkey.
  • Berber I; Malatya Training and Research Hospital, Division of Hematology, Malatya, Turkey.
  • Dogu MH; Istanbul Training and Research Hospital, Hematology Clinic, Istanbul, Turkey.
  • Gulturk E; Kartal Dr. Lutfi Kirdar Training and Research Hospital, Department of Internal Medicine, Division of Hematology, Istanbul, Turkey.
  • Ulas T; Near East University, Department of Internal Medicine, Division of Hematology, Nicosia, Cyprus.
  • Payzin B; Izmir Katip Celebi University, Ataturk Training and Research Hospital, Department of Hematology, Izmir, Turkey.
  • Kuku I; Inonu University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Malatya, Turkey.
  • Cagirgan S; Adnan Menderes University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Aydin, Turkey.
  • Altuntas F; University of Health Sciences, Ankara Oncology Training and Research Hospital, Department of Hematology and BMT Unit, Ankara, Turkey; Yildirim Beyazit University, Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Ankara, Turkey.
Transfus Apher Sci ; 58(3): 287-292, 2019 Jun.
Article en En | MEDLINE | ID: mdl-31036516
Therapeutic plasma exchange (TPE) is used to treat more than 60 diseases worldwide and has drawn growing interest. Little is known about the current situation of TPE activity in Turkey, so we developed a survey to obtain information about this timely topic. We collected data on TPE from 28 apheresis units throughout Turkey. We performed a total of 24,912 TPE procedures with 3203 patients over the past decade. Twenty years ago, the majority of procedures were performed for neurological and hematological disorders, and today, most TPE procedures are done for the same reasons. The only historical change has been an increase in TPE procedures in renal conditions. Currently, renal conditions were more frequently an indication for TPE than rheumatic conditions. Fresh frozen plasma was the most frequently used replacement fluid, followed by 5% albumin, used in 57.9% and 34.6% of procedures, respectively. The most frequently used anticoagulants in TPE were ACD-A and heparin/ACD-A, used with 1671 (52.2%) and 1164 (36.4%) patients, respectively. The frequency of adverse events (AEs) was 12.6%. The most common AEs were hypocalcemia-related symptoms, hypotension, and urticaria. We encountered no severe AEs that led to severe morbidity and mortality. Overall, more than two thirds of the patients showed improvement in the underlying disease. Here, we report on a nationwide survey on TPE activity in Turkey. We conclude that there has been a great increase in apheresis science, and the number of TPE procedures conducted in Turkey has increased steadily over time. Finally, we would like to point out that our past experiences and published international guidelines were the most important tools in gaining expertise regarding TPE.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasma / Intercambio Plasmático / Eliminación de Componentes Sanguíneos / Enfermedades Hematológicas / Anticoagulantes / Enfermedades del Sistema Nervioso Tipo de estudio: Etiology_studies / Guideline / Qualitative_research Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Transfus Apher Sci Asunto de la revista: HEMATOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasma / Intercambio Plasmático / Eliminación de Componentes Sanguíneos / Enfermedades Hematológicas / Anticoagulantes / Enfermedades del Sistema Nervioso Tipo de estudio: Etiology_studies / Guideline / Qualitative_research Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Transfus Apher Sci Asunto de la revista: HEMATOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido