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Efficacy and safety of endoscopic submucosal dissection for non-ampullary duodenal polyps: A systematic review and meta-analysis.
Watanabe, Daisuke; Hayashi, Hiroki; Kataoka, Yuki; Hashimoto, Tadayuki; Ichimasa, Katsuro; Miyachi, Hideyuki; Tanaka, Shinwa; Toyonaga, Takashi.
Afiliación
  • Watanabe D; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.
  • Hayashi H; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.
  • Kataoka Y; Hospital Care Research Unit/Department of Respiratory Medicine, Hyogo Prefectural Amagasaki General Medical Center, Japan. Electronic address: youkiti@gmail.com.
  • Hashimoto T; Hashimoto Municipal Hospital, Japan.
  • Ichimasa K; Digestive Disease Center, Showa University, Northern Yokohama Hospital, Japan.
  • Miyachi H; Department of Gastroenterology, Kakogawa Central City Hospital, Japan.
  • Tanaka S; Department of Endoscopic Medicine, Kobe University Hospital, Japan.
  • Toyonaga T; Department of Endoscopic Medicine, Kobe University Hospital, Japan.
Dig Liver Dis ; 51(6): 774-781, 2019 06.
Article en En | MEDLINE | ID: mdl-31014942
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is commonly used to treat early-stage digestive cancer because it results in a higher frequency of en-bloc resection and a lower frequency of local recurrence. However, the efficacy and safety of duodenal ESD remain unclear. Therefore, present study is aimed at evaluating clinical outcomes of duodenal ESD. METHODS: To evaluate the efficacy and safety of duodenal ESD, electronic databases (MEDLINE, CENTRAL and EMBASE) were searched by two independent reviewers. The authors were contacted for additional information. A meta-analysis was performed to evaluate the efficacy and safety of duodenal ESD. RESULTS: A total of 7 studies (203 patients) were included in the quantitative synthesis analysis. The pooled proportions of the frequencies of en-bloc resection, need for surgical intervention, bleeding, intraoperative perforation and delayed perforation were 87%, 4%, 2%, 15% and 2%, respectively. The quality of evidence regarding on surgical intervention outcomes was rated as moderate, whereas that of en-bloc resection was rated as low because of its marked inconsistency. CONCLUSIONS: Duodenal ESD produced acceptable outcomes in terms of the en-bloc R0 resection, but the incidence of procedure-related adverse events is high (PROSPERO register, CRD42017057110).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pólipos Intestinales / Duodeno / Resección Endoscópica de la Mucosa / Mucosa Intestinal Tipo de estudio: Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Dig Liver Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pólipos Intestinales / Duodeno / Resección Endoscópica de la Mucosa / Mucosa Intestinal Tipo de estudio: Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Dig Liver Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos