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Trends of blood-borne infectious diseases in a rural blood donation center of southeast Gabon (Koula-Moutou).
Bisseye, Cyrille; Mombo, Landry-Erik; Bie, Stéphane Meyet Me; Edou, Apollinaire; Eko-Mba, Jean Marie; Etho-Mengue, Jean-Charles; Mbacky, Kévin; Mongo-Delis, Arnaud; M'batchi, Bertrand; Nagalo, Bolni Marius.
Afiliación
  • Bisseye C; Laboratoire de Biologie Moléculaire et Cellulaire (LABMC), Université des Sciences et Techniques de Masuku, BP 943, Franceville, Gabon.
  • Mombo LE; Laboratoire de Biologie Moléculaire et Cellulaire (LABMC), Université des Sciences et Techniques de Masuku, BP 943, Franceville, Gabon.
  • Bie SMM; Laboratoire de Biologie Moléculaire et Cellulaire (LABMC), Université des Sciences et Techniques de Masuku, BP 943, Franceville, Gabon.
  • Edou A; Centre Hospitalier Régional Paul Moukambi (CHRPM), BP 03 Koula-Moutou, Gabon.
  • Eko-Mba JM; Centre Hospitalier Régional Paul Moukambi (CHRPM), BP 03 Koula-Moutou, Gabon.
  • Etho-Mengue JC; Laboratoire de Biologie Moléculaire et Cellulaire (LABMC), Université des Sciences et Techniques de Masuku, BP 943, Franceville, Gabon.
  • Mbacky K; Centre Hospitalier Régional Paul Moukambi (CHRPM), BP 03 Koula-Moutou, Gabon.
  • Mongo-Delis A; Centre Hospitalier Régional Paul Moukambi (CHRPM), BP 03 Koula-Moutou, Gabon.
  • M'batchi B; Centre de Traitement ambulatoire de Koula-Moutou, BP 383 Koula-Moutou, Gabon.
  • Nagalo BM; Laboratoire de Biologie Moléculaire et Cellulaire (LABMC), Université des Sciences et Techniques de Masuku, BP 943, Franceville, Gabon.
Pan Afr Med J ; 31: 81, 2018.
Article en En | MEDLINE | ID: mdl-31007828
INTRODUCTION: Blood-borne pathogens such as human immunodeficiency virus (HIV), hepatitis B and C (HBV and HCV) viruses and Treponema pallidum remain a major public health problem in sub-Saharan Africa. The purpose of this study was to assess the frequency and clinical implications of HIV, HBV, HCV and Treponema pallidum markers in blood donors in a rural area of Southeast Gabon (Koula-Moutou) from 2012 to 2017. METHODS: Hepatitis B surface antigen (HBsAg), anti-HIV, anti-HCV and anti-Treponema pallidum antibodies were screened using rapid diagnostic tests (RDTs). RESULTS: Of a total of 5,706 blood donors, 1,054 (18.5%) were seropositive for at least one infectious marker and 59 (5.6%) had serologic evidence of multiple infections. The overall seroprevalence of HIV, HBsAg, HCV, and syphilis was 3.1%; 5.9%; 6.2% and 3.3%, respectively. HIV, syphilis and HCV distributions were associated with neither the sex nor the age of the donors. Only HBsAg seroprevalence was significantly higher in donors of the age group 26-35 years old compared to donors of the age group 36-45 years (OR = 1.43 (95% CI: 1.01-2.04), P = 0.045). There was a significant increase in the frequencies of HIV and syphilis and a regression of HBsAg and HCV among blood donors. CONCLUSION: This study presents the epidemiology of the main pathogens detected in blood donors in a rural area in Gabon. We found that the overall distribution of transfusion transmitted infectious diseases were lower than those observed in the general population but could be underestimated due to the use of RDTs in the screening process of the blood donations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Población Rural / Donantes de Sangre / Tamizaje Masivo / Patógenos Transmitidos por la Sangre Tipo de estudio: Screening_studies Aspecto: Determinantes_sociais_saude Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: Pan Afr Med J Año: 2018 Tipo del documento: Article País de afiliación: Gabón Pais de publicación: Uganda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Población Rural / Donantes de Sangre / Tamizaje Masivo / Patógenos Transmitidos por la Sangre Tipo de estudio: Screening_studies Aspecto: Determinantes_sociais_saude Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: Pan Afr Med J Año: 2018 Tipo del documento: Article País de afiliación: Gabón Pais de publicación: Uganda