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Expert Opinion: Use of sodium glucose co-transporter type-2 inhibitors in South Asian population -The Pakistan perspective.
Raza, Syed Abbas; Aamir, A H; Jawa, Ali; Qureshi, Faisal Masood; Ahmad, Ibrar; Khan, Khalid Mahmud; Khan, Khursheed; Naseer, Nauman; Islam, Najmul; Ishtiaq, Osama; Mahar, Saeed Ahmed.
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  • Raza SA; Shaukat Khanum Cancer Hospital and Research Center. Johar Town, Lahore, Punjab. Pakistan.
  • Aamir AH; Hayatabad Medical Complex Peshawar. Pakistan.
  • Jawa A; Wilshire Cardiovascular and Endocrine Center of Excellence WILCARE Lahore.
  • Qureshi FM; Al Khaliq Hospital, Multan.
  • Ahmad I; Lady Reading Hospital Peshawar.
  • Khan KM; Allama Iqbal Medical College Lahore.
  • Khan K; Allama Iqbal Medical College Lahore.
  • Naseer N; Akhtar Saeed Medical College, Lahore.
  • Islam N; AKUH Karachi.
  • Ishtiaq O; Shifa International Hospital Islamabad.
  • Mahar SA; National Institute of Cardiovascular Diseases Karachi, Pakistan.
J Pak Med Assoc ; 69(4): 555-563, 2019 Apr.
Article en En | MEDLINE | ID: mdl-31000862
Sodium-glucose co-transporter type 2 inhibitors (SGLT 2- i)are increasingly being used in the management of type 2 diabetes mellitus (T2DM). With the novel insulinindependent glycosuric action, these agents help to attain glycaemic goals by lowering HbA1c and fasting blood glucose. In addition, these agents improve metabolic control in diabetes and ameliorate comorbidities like obesity and hyper tension. Beneficial effec ts on cardiovascular outcomes have been a key attraction for physicians. These agents are used alone or in combination with oral antidiabetic agents and insulin to attain glycaemic and metabolic targets. A major disadvantagewith these agents is the increased risk for genital andurinary infections. When used in appropriate settings, there is no additional increased risk of hypoglycaemia or volume depletion with these agents. Available evidence suggests good efficacy and safety of these agents in diabetes management. The easy and convenient oncedaily dosing should be customized according to patient needs and glycaemic profiles.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pueblo Asiatico / Diabetes Mellitus Tipo 2 / Inhibidores del Cotransportador de Sodio-Glucosa 2 Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Pak Med Assoc Año: 2019 Tipo del documento: Article Pais de publicación: Pakistán
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pueblo Asiatico / Diabetes Mellitus Tipo 2 / Inhibidores del Cotransportador de Sodio-Glucosa 2 Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Pak Med Assoc Año: 2019 Tipo del documento: Article Pais de publicación: Pakistán