Attenuation of a dengue virus replicon by codon deoptimization of nonstructural genes.

Manokaran, Gayathri; McPherson, Kirsty Grace; Simmons, Cameron Paul

Manokaran, Gayathri; McPherson, Kirsty Grace; Simmons, Cameron Paul.

Afiliación

Manokaran G; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia; Institute of Vector Borne Disease, Monash University, Clayton, Victoria, Australia.
Sujatmoko; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
McPherson KG; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Simmons CP; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia; Institute of Vector Borne Disease, Monash University, Clayton, Victoria, Australia; Oxford University Clinical Research Unit, Wellcome Trust Major O

Vaccine ; 37(21): 2857-2863, 2019 05 09.

Article en En | MEDLINE | ID: mdl-31000413

Asunto(s)

Codón/genética; Virus del Dengue/genética; Replicón/genética; Proteínas no Estructurales Virales/genética; Animales; Línea Celular; Cricetinae; Electroporación; Replicación Viral/genética; Replicación Viral/fisiología

Palabras clave

Attenuation; Codon deoptimization; Dengue; Replicon; Vaccine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Replicón / Codón / Proteínas no Estructurales Virales / Virus del Dengue Límite: Animals Idioma: En Revista: Vaccine Año: 2019 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Países Bajos

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