Interactions between Clotrimazole and selected essential oils against Malassezia pachydermatis clinical isolates.
Pol J Vet Sci
; 22(1): 173-175, 2019 Mar.
Article
en En
| MEDLINE
| ID: mdl-30997781
The aim of this study was to investigate interactions between conventional antifungal drug and essential oils against isolates of Malassezia pachydermatis. Antifungal activity of Cinnamomum cassia, Melaleuca alternifolia, Mentha piperita, Origanum vulgare and Syzygium aromaticum essential oils were tested against 19 strains of M. pachydermatis isolated from healthy dogs and reference strain M. pachydermatis CBS 1879. The checkerboard assay was used to search for in- teractions. Synergism was observed for the combination of clotrimazole with Melaleuca alternifolia essential oil, Mentha piperita and Origanum vulgare. The combinations of Cinnamomum cassia and Syzygium aromaticum essential oils with clotrimazole showed indifferent effect. Additive antimicrobial activity was observed for the combination of clotrimazole with Syzygium aromaticum and Melaleuca alternifolia essential oils against reference strain. The obtained results showed synergistic interactions between essential oils and clotrimazole which could improve effectiveness of this antifungal drug.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aceites de Plantas
/
Aceites Volátiles
/
Clotrimazol
/
Malassezia
/
Antifúngicos
Idioma:
En
Revista:
Pol J Vet Sci
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2019
Tipo del documento:
Article
Pais de publicación:
Alemania