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Addressing the properties of "Metallo-DNA" with a Ag(i)-mediated supramolecular duplex.
Mistry, Liam; El-Zubir, Osama; Dura, Gema; Clegg, William; Waddell, Paul G; Pope, Thomas; Hofer, Werner A; Wright, Nick G; Horrocks, Benjamin R; Houlton, Andrew.
Afiliación
  • Mistry L; Chemical Nanoscience Laboratory , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK . Email: Andrew.houlton@ncl.ac.uk.
  • El-Zubir O; Chemical Nanoscience Laboratory , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK . Email: Andrew.houlton@ncl.ac.uk.
  • Dura G; Chemical Nanoscience Laboratory , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK . Email: Andrew.houlton@ncl.ac.uk.
  • Clegg W; Chemistry , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK.
  • Waddell PG; Chemistry , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK.
  • Pope T; Chemistry , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK.
  • Hofer WA; Chemistry , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK.
  • Wright NG; School of Engineering , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK.
  • Horrocks BR; Chemical Nanoscience Laboratory , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK . Email: Andrew.houlton@ncl.ac.uk.
  • Houlton A; Chemical Nanoscience Laboratory , School of Natural & Environmental Sciences , Newcastle University , Newcastle upon Tyne , NE1 7RU , UK . Email: Andrew.houlton@ncl.ac.uk.
Chem Sci ; 10(11): 3186-3195, 2019 Mar 21.
Article en En | MEDLINE | ID: mdl-30996900
The silver-nucleoside complex [Ag(i)-(N3-cytidine)2], 1, self-assembles to form a supramolecular metal-mediated base-pair array highly analogous to those seen in metallo-DNA. A combination of complementary hydrogen-bonding, hydrophobic and argentophilic interactions drive the formation of a double-helix with a continuous silver core. Electrical measurements on 1 show that despite having Ag···Ag distances within <5% of the metallic radii, the material is electrically insulating. This is due to the electronic structure which features a filled valence band, an empty conduction band dominated by the ligand, and a band gap of 2.5 eV. Hence, as-prepared, such Ag(i)-DNA systems should not be considered molecular nanowires but, at best, proto-wires. The structural features seen in 1 are essentially retained in the corresponding organogel which exhibits thixotropic self-healing that can be attributed to the reversible nature of the intermolecular interactions. Photo-reduced samples of the gel exhibit luminescence confirming that these poly-cytidine sequences appropriately pre-configure silver ions for the formation of quantum-confined metal clusters in line with contemporary views on DNA-templated clusters. Microscopy data reveals the resulting metal cluster/particles are approximately spherical and crystalline with lattice spacing (111) similar to bulk Ag.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Sci Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Sci Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido