Improved lovastatin production by inhibiting (+)-geodin biosynthesis in Aspergillus terreus.

Hasan, Hanan; Abd Rahim, Muhamad Hafiz; Campbell, Leona; Carter, Dee; Abbas, Ali; Montoya, Alejandro

Hasan, Hanan; Abd Rahim, Muhamad Hafiz; Campbell, Leona; Carter, Dee; Abbas, Ali; Montoya, Alejandro.

Afiliación

Hasan H; The University of Sydney, School of Chemical and Biomolecular Engineering, Australia; Universiti Putra Malaysia, Faculty of Food Science and Technology, Malaysia. Electronic address: mhanan@upm.edu.my.
Abd Rahim MH; The University of Sydney, School of Chemical and Biomolecular Engineering, Australia; Universiti Putra Malaysia, Faculty of Food Science and Technology, Malaysia.
Campbell L; The University of Sydney, School of Life and Environmental Sciences, Australia.
Carter D; The University of Sydney, School of Life and Environmental Sciences, Australia.
Abbas A; The University of Sydney, School of Chemical and Biomolecular Engineering, Australia.
Montoya A; The University of Sydney, School of Chemical and Biomolecular Engineering, Australia.

N Biotechnol ; 52: 19-24, 2019 Sep 25.

Article en En | MEDLINE | ID: mdl-30995533

Asunto(s)

Aspergillus/metabolismo; Benzofuranos/metabolismo; Vías Biosintéticas; Lovastatina/biosíntesis; Acetilcoenzima A/biosíntesis; Glicerol/metabolismo; Lactosa/metabolismo; Malonil Coenzima A/biosíntesis

Palabras clave

(+)-Geodin; Aspergillus terreus; Emodin anthrone polyketide synthase; Gene knockout; Lovastatin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspergillus / Benzofuranos / Lovastatina / Vías Biosintéticas Idioma: En Revista: N Biotechnol Asunto de la revista: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Año: 2019 Tipo del documento: Article Pais de publicación: Países Bajos

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