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Hypertension-induced subclinical vascular and cognitive changes are reversible-An observational cohort study.
Czuriga-Kovács, Katalin Réka; Szekeres, Csilla Cecília; Bajkó, Zoltán; Csapó, Krisztina; Oláh, László; Magyar, Mária Tünde; Molnár, Sándor; Czuriga, Dániel; Kardos, László; Bojtor Burainé, Andrea; Bereczki, Dániel; Soltész, Pál; Csiba, László.
Afiliación
  • Czuriga-Kovács KR; Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Szekeres CC; Department of Neurology, Elisabeth Teaching Hospital of Sopron, Sopron, Hungary.
  • Bajkó Z; Department of Neurology, Mures County Clinical Emergency Hospital, Târgu-Mureș, Romania.
  • Csapó K; Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Oláh L; Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Magyar MT; Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Molnár S; Department of Neurology, Elisabeth Teaching Hospital of Sopron, Sopron, Hungary.
  • Czuriga D; Division of Cardiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Kardos L; Kenézy Gyula University Hospital, University of Debrecen, Debrecen, Hungary.
  • Bojtor Burainé A; Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Bereczki D; Department of Neurology, Semmelweis University, Budapest, Hungary.
  • Soltész P; Division of Angiology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Csiba L; Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
J Clin Hypertens (Greenwich) ; 21(5): 658-667, 2019 05.
Article en En | MEDLINE | ID: mdl-30980603
Beside the well-known complications of poorly controlled, long-standing hypertension, milder abnormalities induced by early-stage hypertension have also been described. In our study, the authors examined the reversibility of changes induced by early-stage hypertension. The authors performed laboratory testing, ambulatory blood pressure monitoring, carotid intima-media thickness (IMT) measurement, evaluation of stiffness parameters, assessment of various cardiac and cerebral hemodynamic parameters during head-up tilt table (HUTT) testing, and neuropsychological examinations in 49 recently diagnosed hypertensive patients. Following baseline assessment, antihypertensive therapy was commenced. After one year of therapy, lower IMT values were found. Pulse wave velocity showed a borderline significant decrease. During HUTT, several hemodynamic parameters improved. The patients performed better on neuropsychological testing and reached significantly lower scores on questionnaires evaluating anxiety. The present study shows that early vascular changes and altered cognitive function observed in newly diagnosed hypertensive patients may improve with promptly initiated antihypertensive management.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cognición / Hipertensión Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Clin Hypertens (Greenwich) Asunto de la revista: ANGIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cognición / Hipertensión Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Clin Hypertens (Greenwich) Asunto de la revista: ANGIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Estados Unidos