ALT, alanine transaminase; AST, aspartate transaminase; AUC, area under the curve; Antitumor efficacy; BUN, blood urea nitrogen; C-6, coumarin-6; CREA, creatinine; DDS, drug delivery system; DMSO, dimethyl sulfoxide; DSPE-PEG2K, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethyleneglycol)-2000]; DTT, d,l-dithiothreitol; DTX, docetaxel; Docetaxel; EDCI, N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride; FBS, fetal bovine serum; GSH, glutathione; H2O2, hydrogen peroxide; HOBt, 1-hydroxybenzotriazole monohydrate; HPLC, high-performance liquid chromatography; IC50, half maximal inhibitory concentration; LA, linoleic acid; Linoleic acid; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; Mono thioether bond; Nanoassemblies; PBS, phosphate buffer saline; PDI, polydispersity index; PTX, paclitaxel; Pharmacokinetics; ROS, reactive oxygen species; SD, standard deviation; TLC, thin layer chromatography