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Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase.
Jani, Krupa S; Jain, Siddhant U; Ge, Eva J; Diehl, Katharine L; Lundgren, Stefan M; Müller, Manuel M; Lewis, Peter W; Muir, Tom W.
Afiliación
  • Jani KS; Department of Chemistry, Princeton University, Princeton, NJ 08544.
  • Jain SU; Wisconsin Institute of Discovery, University of Wisconsin, Madison, WI 53715.
  • Ge EJ; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715.
  • Diehl KL; Department of Chemistry, Princeton University, Princeton, NJ 08544.
  • Lundgren SM; Department of Chemistry, Princeton University, Princeton, NJ 08544.
  • Müller MM; Wisconsin Institute of Discovery, University of Wisconsin, Madison, WI 53715.
  • Lewis PW; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715.
  • Muir TW; Department of Chemistry, Princeton University, Princeton, NJ 08544.
Proc Natl Acad Sci U S A ; 116(17): 8295-8300, 2019 04 23.
Article en En | MEDLINE | ID: mdl-30967505

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histonas / Proteína Potenciadora del Homólogo Zeste 2 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histonas / Proteína Potenciadora del Homólogo Zeste 2 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos