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Authentication of Rhodiola rosea, Rhodiola quadrifida and Rhodiola rosea liquid extract from the Ukrainian market using HPTLC chromatographic profiles.
Khokhlova, Kateryna; Zdoryk, Oleksandr.
Afiliación
  • Khokhlova K; Department of Technology of Drugs, National University of Pharmacy , Kharkiv , Ukraine.
  • Zdoryk O; Department of Quality, Standardization and Certification of Drugs, National University of Pharmacy , Kharkiv , Ukraine.
Nat Prod Res ; 34(19): 2842-2846, 2020 Oct.
Article en En | MEDLINE | ID: mdl-30919667
Rhodiola rosea and Rhodiola quadrifida are widely distributed and sold in Eastern Europe. The purpose of this paper was to identify R.rosea, R.quadrifida and Rhodiola rosea liquid extract (RRLE) in the Ukrainian market and bring out adulteration cases using chromatographic characterisation by HPTLC. The multiple samples of R.rosea, R.quadrifida and RRLE were compared; the optimal chromatographic conditions for identification of R.rosea and RRLE based on the presence of rosavins and salidroside as well as for identification of R.quadrifida based on the presence of salidroside were proposed; the specific HPTLC fingerprints were obtained; the acceptance criteria for each product were set. The adulteration cases for R.rosea and RRLE samples were established. The dependence on handling R.rosea and presence of rosavins was determined. It was assumed that low-quality raw materials or inefficient technology process were used for RRLE. The consistency of HPTLC fingerprints for R.quadrifida samples was established.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Contaminación de Medicamentos / Cromatografía en Capa Delgada / Rhodiola Tipo de estudio: Prognostic_studies País/Región como asunto: Europa Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Contaminación de Medicamentos / Cromatografía en Capa Delgada / Rhodiola Tipo de estudio: Prognostic_studies País/Región como asunto: Europa Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Reino Unido