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Detoxification of the T2 fraction from a scorpion (Tityus serrulatus, Lutz and Mello) venom by iodination and some immunogenic properties of the derivatives.
Toxicon ; 24(5): 501-5, 1986.
Article en En | MEDLINE | ID: mdl-3087032
The iodination of the T2 fraction abolished its lethal capacity, and doses up to 30 times the LD50 were injected i.p. in mice without noticeable toxic effects. The modified fraction retained its immunological properties. Antibodies generated against the iodinated T2 fraction were also reactive toward the native T2 fraction, T1 fraction and the whole soluble venom.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Venenos de Escorpión Límite: Animals Idioma: En Revista: Toxicon Año: 1986 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Venenos de Escorpión Límite: Animals Idioma: En Revista: Toxicon Año: 1986 Tipo del documento: Article Pais de publicación: Reino Unido