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Advancement in TPL2-regulated innate immune response.
Yan, Ming-Hao; Hao, Jun-Hong; Zhang, Xue-Gang; Shen, Chao-Chao; Zhang, Da-Jun; Zhang, Ke-Shan; Zheng, Hai-Xue; Liu, Xiang-Tao.
Afiliación
  • Yan MH; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China.
  • Hao JH; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China.
  • Zhang XG; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China.
  • Shen CC; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China.
  • Zhang DJ; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China.
  • Zhang KS; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China. Electronic address: zks009@126.com.
  • Zheng HX; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China. Electronic address: zhenghaixue@caas.cn.
  • Liu XT; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 73004, China.
Immunobiology ; 224(3): 383-387, 2019 05.
Article en En | MEDLINE | ID: mdl-30853309
Tumor progression locus 2 (TPL2) is a serine/threonine kinase that belongs to the MAP3K family. The activated TPL2 regulates the innate immune-relevant signaling pathways, such as ERK, JNK, and NF-κB, and the differentiation of immune cells, for example, CD4+ T and NK cells. Therefore, TPL2 plays a critical role in regulating the innate immune response. The present review summarizes the recent advancements in the TPL2-regulated innate immune response.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Proteínas Proto-Oncogénicas / Quinasas Quinasa Quinasa PAM Límite: Animals / Humans Idioma: En Revista: Immunobiology Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Proteínas Proto-Oncogénicas / Quinasas Quinasa Quinasa PAM Límite: Animals / Humans Idioma: En Revista: Immunobiology Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos