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Mid-term outcome of severe tricuspid regurgitation: are there any differences according to mechanism and severity?
Santoro, Ciro; Marco Del Castillo, Alvaro; González-Gómez, Ariana; Monteagudo, Juan Manuel; Hinojar, Rocio; Lorente, Alvaro; Abellás, María; Vieitez, Jose Maria; Garcia Martìn, Ana; Casas Rojo, Eduardo; Ruíz, Soledad; Barrios, Vivencio; Luis Moya, Jose; Jimenez-Nacher, Jose Julio; Zamorano Gomez, Jose Luis; Fernández-Golfín, Covadonga.
Afiliación
  • Santoro C; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Marco Del Castillo A; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • González-Gómez A; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Monteagudo JM; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • Hinojar R; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Lorente A; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • Abellás M; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Vieitez JM; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • Garcia Martìn A; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Casas Rojo E; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • Ruíz S; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Barrios V; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • Luis Moya J; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Jimenez-Nacher JJ; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
  • Zamorano Gomez JL; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.
  • Fernández-Golfín C; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
Eur Heart J Cardiovasc Imaging ; 20(9): 1035-1042, 2019 Sep 01.
Article en En | MEDLINE | ID: mdl-30830219
AIMS: Patients with significant tricuspid regurgitation (TR) addressed according the new classification in torrential TR may have different prognosis compared with just severe TR patients. We sought to determine distribution and mechanism of consecutive severe TR patients, in accordance with aetiology and severity by applying the new proposed classification scheme and their long-term outcomes. METHODS AND RESULTS: Between January and December 2013, 249 patients with significant TR referred to the cardiac imaging unit (mean age 79.9 ± 10.2 years; 29.8% female) were included. Patients were divided according to aetiology in six groups, and TR severity was reclassified into severe, massive, and torrential TR. The follow-up period was of 313 ± 103 days. When considering cardiovascular mortality, patients in the massive/torrential group showed the highest number of events (P < 0.007). Patients with TR due to pulmonary diseases had the worst prognosis according to different aetiology. Noteworthy, the best predictors for the combined endpoint [cardiovascular mortality and readmission admission for heart failure (HF)] were TR severity according to the new classification [hazard ratio (HR) 2.48, 95% confidence interval (CI) 1.25-4.93] and clinical scores such as New York Heart Association classification and congestive status (HR 1.78, 95% CI 1.28-2.49; HR 2.08, 95% CI 1.06-4.06, respectively). CONCLUSION: Patients with massive/torrential TR and patients with comorbidities, especially pulmonary disease, were identified as populations at higher risk of death and readmission for HF. New classification scheme and clinical assessment may establish who may benefit the most of intensive therapeutic treatments and intervention on the tricuspid valve.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia de la Válvula Tricúspide / Ecocardiografía Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Eur Heart J Cardiovasc Imaging Año: 2019 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia de la Válvula Tricúspide / Ecocardiografía Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Eur Heart J Cardiovasc Imaging Año: 2019 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido