Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.

Rogers, Julia M; Waters, Colin T; Seegar, Tom C M; Jarrett, Sanchez M; Hallworth, Amelia N; Blacklow, Stephen C; Bulyk, Martha L

Rogers, Julia M; Waters, Colin T; Seegar, Tom C M; Jarrett, Sanchez M; Hallworth, Amelia N; Blacklow, Stephen C; Bulyk, Martha L.

Afiliación

Rogers JM; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Committee on Higher Degrees in Biophysics, Harvard University, Cambridge, MA 02138, USA.
Waters CT; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA 02138, USA.
Seegar TCM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Jarrett SM; Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Hallworth AN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Blacklow SC; Committee on Higher Degrees in Biophysics, Harvard University, Cambridge, MA 02138, USA; Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Departme
Bulyk ML; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Committee on Higher Degrees in Biophysics, Harvard University, Cambridge, MA 02138, USA; Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA 0213

Mol Cell ; 74(2): 245-253.e6, 2019 04 18.

Article en En | MEDLINE | ID: mdl-30826165

Asunto(s)

Proteínas de Ciclo Celular/química; Proteínas de Unión al ADN/química; ADN/química; Conformación de Ácido Nucleico; Proteínas Represoras/química; Secuencia de Aminoácidos/genética; Secuencia de Bases/genética; Sitios de Unión/genética; Proteínas de Ciclo Celular/genética; Cristalografía por Rayos X; ADN/genética; Proteínas de Unión al ADN/genética; Factores de Transcripción Forkhead; Regulación de la Expresión Génica/genética; Humanos; Complejos Multiproteicos/química; Complejos Multiproteicos/genética; Motivos de Nucleótidos/genética; Secuencias Reguladoras de Ácidos Nucleicos/genética; Proteínas Represoras/genética

Palabras clave

DNA binding sites; DNA shape; co-crystal structures; forkhead; gene regulation; protein-DNA interactions; specificity; transcription factors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Represoras / ADN / Proteínas de Ciclo Celular / Proteínas de Unión al ADN / Conformación de Ácido Nucleico Límite: Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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