Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape.

Vlachavas, Efstathios-Iason; Pilalis, Eleftherios; Papadodima, Olga; Koczan, Dirk; Willis, Stefan; Klippel, Sven; Cheng, Caixia; Pan, Leyun; Sachpekidis, Christos; Pintzas, Alexandros; Gregoriou, Vasilis; Dimitrakopoulou-Strauss, Antonia; Chatziioannou, Aristotelis

Vlachavas, Efstathios-Iason; Pilalis, Eleftherios; Papadodima, Olga; Koczan, Dirk; Willis, Stefan; Klippel, Sven; Cheng, Caixia; Pan, Leyun; Sachpekidis, Christos; Pintzas, Alexandros; Gregoriou, Vasilis; Dimitrakopoulou-Strauss, Antonia; Chatziioannou, Aristotelis.

Afiliación

Vlachavas EI; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.
Pilalis E; Department of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Dragana, Greece.
Papadodima O; Enios Applications Private Limited Company, A17671 Athens, Greece.
Koczan D; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.
Willis S; Enios Applications Private Limited Company, A17671 Athens, Greece.
Klippel S; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.
Cheng C; Core Facility Micro-Array-Technology, Center of Medical Research, University of Rostock, Germany.
Pan L; Surgical Clinic A, Klinikum Ludwigshafen, Germany.
Sachpekidis C; Surgical Clinic A, Klinikum Ludwigshafen, Germany.
Pintzas A; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany.
Gregoriou V; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany.
Dimitrakopoulou-Strauss A; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany.
Chatziioannou A; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.

Comput Struct Biotechnol J ; 17: 177-185, 2019.

Article en En | MEDLINE | ID: mdl-30809322

Palabras clave

18F-FDG PET; ACADM, Acyl-Coenzyme A Dehydrogenase; AUC, Area Under the Curve; CCT7, Chaperonin Containing TCP1 Subunit 7; CD44, CD44 Molecule (Indian Blood Group); CRC, Colorectal cancer; Colorectal cancer; DE, Differentially Expressed; FD, Fractal Dimension; FDG, F-18-Fluorodeoxyglucose; GDC, Genomics Data Commons; GEO, Gene Expression Omnibus; GSTP1, Glutathione S-Transferase Pi 1; KIT, Proto-Oncogene Receptor Tyrosine Kinase; Lasso, least absolute shrinkage and selection operator; MFA, Multiple Factor Analysis; Microarray analysis; PCs, Principal Components; PET, Positron Emission Tomography; ROC, Receiver-operator Characteristic curve; Radiogenomics; SUV, Standardized Uptake Value; TCGA; TCGA-COAD, The Cancer Genome Atlas-Colon Adenocarcinoma; Translational bioinformatics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Comput Struct Biotechnol J Año: 2019 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Países Bajos

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