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Discovery of the Biginelli hybrids as novel caspase-9 activators in apoptotic machines: Lipophilicity, molecular docking study, influence on angiogenesis gene and miR-21 expression levels.
Jankovic, Nenad; Trifunovic Ristovski, Jovana; Vranes, Milan; Tot, Aleksandar; Petronijevic, Jelena; Joksimovic, Nenad; Stanojkovic, Tatjana; Dordic Crnogorac, Marija; Petrovic, Nina; Boljevic, Ivana; Matic, Ivana Z; Bogdanovic, Goran A; Mikov, Momir; Bugarcic, Zorica.
Afiliación
  • Jankovic N; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, 34000 Kragujevac, Serbia. Electronic address: nenad.jankovic@kg.ac.rs.
  • Trifunovic Ristovski J; Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
  • Vranes M; Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia.
  • Tot A; Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia.
  • Petronijevic J; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
  • Joksimovic N; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
  • Stanojkovic T; Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia.
  • Dordic Crnogorac M; Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia.
  • Petrovic N; Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia; Vinca Institute of Nuclear Science, University of Belgrade, P.O. Box 522, 11001 Belgrade, Serbia.
  • Boljevic I; Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia.
  • Matic IZ; Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia.
  • Bogdanovic GA; Vinca Institute of Nuclear Science, University of Belgrade, P.O. Box 522, 11001 Belgrade, Serbia.
  • Mikov M; Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
  • Bugarcic Z; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
Bioorg Chem ; 86: 569-582, 2019 05.
Article en En | MEDLINE | ID: mdl-30782575
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / MicroARNs / Caspasa 9 / Descubrimiento de Drogas / Simulación del Acoplamiento Molecular / Neovascularización Patológica / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / MicroARNs / Caspasa 9 / Descubrimiento de Drogas / Simulación del Acoplamiento Molecular / Neovascularización Patológica / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos