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Efficacy and safety of AZD7594, an inhaled non-steroidal selective glucocorticoid receptor modulator, in patients with asthma: a phase 2a randomized, double blind, placebo-controlled crossover trial.
Brown, Mary N; Fuhr, Rainard; Beier, Jutta; Su, Hong-Lin; Chen, Yingxue; Forsman, Henrik; Hamrén, Ulrika Wählby; Jackson, Helen; Aggarwal, Ajay.
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  • Brown MN; Respiratory, Inflammation and Autoimmunity Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, 35 Gatehouse Drive, Waltham, MA, 02451, USA. mary.brown@astrazeneca.com.
  • Fuhr R; PAREXEL, International GmbH House 18, Klinikum Westend, Spandauer Damm 130, 14050, Berlin, Germany.
  • Beier J; insaf - Respiratory Research Institute GmbH, Villa Berg Biebricher Allee 34, D-65187, Wiesbaden, Germany.
  • Su HL; Biometrics, Early Clinical Development, IMED Biotech Unit, AstraZeneca, 35 Gatehouse Drive, Waltham, MA, 02451, USA.
  • Chen Y; Quantitative Clinical Pharmacology, Early Clinical Development, IMED Biotech Unit, AstraZeneca, 35 Gatehouse Drive, Waltham, MA, 02451, USA.
  • Forsman H; Respiratory, Inflammation and Autoimmunity Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, SE-43183, Gothenburg, Mölndal, Sweden.
  • Hamrén UW; Quantitative Clinical Pharmacology, Early Clinical Development, IMED Biotech Unit, AstraZeneca, SE-43183, Gothenburg, Mölndal, Sweden.
  • Jackson H; Respiratory, Inflammation and Autoimmunity IMED Biotech Unit, AstraZeneca, SE-43183, Gothenburg, Mölndal, Sweden.
  • Aggarwal A; Respiratory, Inflammation and Autoimmunity Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, 35 Gatehouse Drive, Waltham, MA, 02451, USA.
Respir Res ; 20(1): 37, 2019 Feb 18.
Article en En | MEDLINE | ID: mdl-30777086
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Broncodilatadores / Receptores de Glucocorticoides Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Res Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Broncodilatadores / Receptores de Glucocorticoides Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Res Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido