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Associations between serum 25-hydroxyvitamin D3 level and skeletal muscle mass and lower limb muscle strength in Japanese middle-aged subjects.
Kuwabara, Akiko; Tsugawa, Naoko; Kondo, Hiroshi; Ao, Misora; Fujiwara, Hitomi; Hosokawa, Natsuki; Matsumoto, Shiho; Tanaka, Kiyoshi; Nakano, Tetsuo.
Afiliación
  • Kuwabara A; Department of Health and Nutrition, Osaka Shoin Women's University, 4-2-26 Hishiyanishi, Higashiosaka, Osaka 577-8550, Japan.
  • Tsugawa N; Department of Health and Nutrition, Osaka Shoin Women's University, 4-2-26 Hishiyanishi, Higashiosaka, Osaka 577-8550, Japan.
  • Kondo H; Department of Orthopaedic Surgery, Tamana Central Hospital, 1950 Naka, Tamana, Kumamoto, 865-0064, Japan.
  • Ao M; Department of Food and Nutrition, Kyoto Women's University, 35 Imakumano-kitahiyoshicho, Higashiyama, Kyoto 605-8501, Japan.
  • Fujiwara H; Department of Health and Nutrition, Osaka Shoin Women's University, 4-2-26 Hishiyanishi, Higashiosaka, Osaka 577-8550, Japan.
  • Hosokawa N; Department of Health and Nutrition, Osaka Shoin Women's University, 4-2-26 Hishiyanishi, Higashiosaka, Osaka 577-8550, Japan.
  • Matsumoto S; Department of Health and Nutrition, Osaka Shoin Women's University, 4-2-26 Hishiyanishi, Higashiosaka, Osaka 577-8550, Japan.
  • Tanaka K; Department of Food and Nutrition, Kyoto Women's University, 35 Imakumano-kitahiyoshicho, Higashiyama, Kyoto 605-8501, Japan.
  • Nakano T; Department of Orthopaedic Surgery, Tamana Central Hospital, 1950 Naka, Tamana, Kumamoto, 865-0064, Japan.
Osteoporos Sarcopenia ; 3(1): 53-58, 2017 Mar.
Article en En | MEDLINE | ID: mdl-30775503
OBJECTIVES: One of the important risk factors of falling is decreased muscle mass and muscle strength. Recently, there has been an increasing concern on the role of vitamin D in muscle strength and physical activity. Aim of our study is to examine the relationships between vitamin D status and muscle mass and muscle strength in middle-aged healthy adults. METHODS: Subjects were 40 healthy volunteers aged 42.0 ± 10.6 years old. Evaluation was made for serum vitamin D3 metabolites including 25-hydroxyvitamin D3 [25(OH)D3] and 24,25-dihydroxyvitamin D3 [24,25(OH)2D3] concentrations, lower limb muscle strength, and dietary intake by food frequency questionnaire. Body composition was measured by dual-energy X-ray absorptiometry (DXA), and appendicular skeletal mass index (ASMI) was calculated as skeletal muscle mass/squared height. RESULTS: 70% of the subjects had vitamin D insufficiency/deficiency (serum total 25(OH)D < 20 ng/mL), and female subjects had significantly lower serum total 25(OH)D level compared with males. Vitamin D insufficiency/deficiency group had significantly higher body fat, lower SMI and muscle strength, probably reflecting higher percentage of female subjects. Serum vitamin D3 metabolites levels were significantly correlated with whole and site-specific ASMI, and lower limb muscle strength, except for the correlation between serum 24,25(OH)2D3 concentration and lower limb muscle strength. In addition, serum 25(OH)D3 level was a positive significant predictor for both ASMI and lower limb muscle strength, while serum 24,25(OH)2D3 level was not their significant predictor. CONCLUSIONS: Serum 25(OH)D3 level was significantly correlated with both skeletal muscle mass and lower limb muscle strength.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Osteoporos Sarcopenia Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Osteoporos Sarcopenia Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos