microRNA-690 regulates induced pluripotent stem cells (iPSCs) differentiation into insulin-producing cells by targeting Sox9.

Xu, Yang; Huang, Yan; Guo, Yibing; Xiong, Yicheng; Zhu, Shajun; Xu, Liancheng; Lu, Jingjing; Li, Xiaohong; Wan, Jian; Lu, Yuhua; Wang, Zhiwei

Xu, Yang; Huang, Yan; Guo, Yibing; Xiong, Yicheng; Zhu, Shajun; Xu, Liancheng; Lu, Jingjing; Li, Xiaohong; Wan, Jian; Lu, Yuhua; Wang, Zhiwei.

Afiliación

Xu Y; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Huang Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Guo Y; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Xiong Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Zhu S; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Xu L; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Lu J; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Li X; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Wan J; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Lu Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Wang Z; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.

Stem Cell Res Ther ; 10(1): 59, 2019 02 15.

Article en En | MEDLINE | ID: mdl-30767782

Asunto(s)

Diabetes Mellitus/genética; Insulina/genética; MicroARNs/genética; Factor de Transcripción SOX9/genética; Regiones no Traducidas 3'/genética; Animales; Diferenciación Celular/genética; Diabetes Mellitus/terapia; Regulación del Desarrollo de la Expresión Génica/genética; Glucosa/metabolismo; Humanos; Células Madre Pluripotentes Inducidas/metabolismo; Insulina/biosíntesis; Células Secretoras de Insulina/metabolismo; Células Secretoras de Insulina/patología; Islotes Pancreáticos/metabolismo; Islotes Pancreáticos/patología; Ratones; ARN Mensajero/genética; Transducción de Señal/genética; Vía de Señalización Wnt/genética

Palabras clave

Differentiation; Induced pluripotent stem cells (iPSCs); Insulin-producing cells (IPCs); Sox9; Wnt signaling pathway; miRNA-690

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: MicroARNs / Diabetes Mellitus / Factor de Transcripción SOX9 / Insulina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Stem Cell Res Ther Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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