[Long-term efficacy of high-dose aerosol corticotherapy in the treatment of severe asthma]. / Efficacité au long cours d'une corticothérapie en aérosol fortement dosé dans le traitement de l'asthme sévère.
Rev Pneumol Clin
; 44(6): 269-72, 1988.
Article
en Fr
| MEDLINE
| ID: mdl-3072651
Forty-five patients with severe, poorly controlled asthma, including 23 corticosteroid-dependent patients, were treated with a preparation of beclomethasone dipropionate aerosol delivering 250 mcg per puff. The daily dose ranged from 1000 to 2000 mcg. The mean follow-up period was 14 +/- 7 months, and 11 patients have now been followed up for more than 2 years. Forty-two patients were improved, and total withdrawal of continuous steroid therapy could be achieved in 13 cases. Treatment remained effective in long term use, provided a minimum of 1000 mcg/day was given. However, despite clinical improvement the obstructive syndrome persisted in 65% of the patients.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asma
/
Beclometasona
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Rev Pneumol Clin
Año:
1988
Tipo del documento:
Article
Pais de publicación:
Francia