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The effect of intravenous adrenaline on electrocardiographic changes during resuscitation in patients with initial pulseless electrical activity in out of hospital cardiac arrest.
Skjeflo, Gunnar Waage; Skogvoll, Eirik; Loennechen, Jan Pål; Olasveengen, Theresa Mariero; Wik, Lars; Nordseth, Trond.
Afiliación
  • Skjeflo GW; Department of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; Department of Anesthesiology, Nordland Hospital, Bodø, Norway. Electronic address: gunnar.w.skjeflo@ntnu.no.
  • Skogvoll E; Department of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; St. Olavs Hospital, Trondheim University Hospital, Department of Anesthesia and Intensive Care Medicine, Trondheim, Norway.
  • Loennechen JP; Department of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; St. Olavs Hospital, Trondheim University Hospital, Department of Cardiology, Trondheim, Norway.
  • Olasveengen TM; Department of Anesthesiology, Oslo University Hospital, Oslo, Norway.
  • Wik L; Norwegian National Advisory Unit on Prehospital Emergency Medicine (NAKOS), Oslo University Hospital, Oslo, Norway.
  • Nordseth T; Department of Circulation and Medical Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; St Olavs Hospital, Trondheim University Hospital, Department of Emergency Medicine and Pre-Hospital Services, Trondheim, Norway.
Resuscitation ; 136: 119-125, 2019 03.
Article en En | MEDLINE | ID: mdl-30708075
INTRODUCTION: Presence of electrocardiographic rhythm in the absence of palpable pulses defines pulseless electrical activity (PEA) and the electrocardiogram (ECG) may provide a source of information during resuscitation. The aim of this study was to examine the development of ECG characteristics during advanced life support (ALS) from Out-of-hospital cardiac arrest (OHCA) with initial PEA, and to explore the potential effects of adrenaline on these characteristics. METHODS: Patients with OHCA and initial PEA, part of randomized controlled trial of ALS with or without intravenous access and medications, were included. A total of 4840 combined observations of QRS complex rate (heart rate) and width were made by examining defibrillator recordings from 170 episodes of cardiac arrest. RESULTS: We found Increased heart rate (47 beats per minute) and reduced QRS complex width (62 ms) during ALS in patients who obtained return of spontaneous circulation (ROSC); while patients who received adrenaline but died increased their heart rate (22 beats per minute) without any concomitant decrease in QRS complex width. CONCLUSION: ECG changes during ALS in cardiac arrest were associated with prognosis, and the administration of adrenaline impacted on these changes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epinefrina / Agonistas Adrenérgicos beta / Apoyo Vital Cardíaco Avanzado / Paro Cardíaco Extrahospitalario Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Resuscitation Año: 2019 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epinefrina / Agonistas Adrenérgicos beta / Apoyo Vital Cardíaco Avanzado / Paro Cardíaco Extrahospitalario Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Resuscitation Año: 2019 Tipo del documento: Article Pais de publicación: Irlanda