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BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Zong, Dali; Adam, Salomé; Wang, Yifan; Sasanuma, Hiroyuki; Callén, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J; Wong, Nancy; Munro, Meagan; Ray Chaudhuri, Arnab; Karim, Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, André.
Afiliación
  • Zong D; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Adam S; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
  • Wang Y; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Sasanuma H; Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Callén E; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Murga M; Genomic Instability Group, Spanish National Cancer Research Center, CNIO, Madrid, Spain.
  • Day A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Kruhlak MJ; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Wong N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Munro M; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
  • Ray Chaudhuri A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Karim B; Pathology/Histotechnology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Xia B; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Takeda S; Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Johnson N; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Durocher D; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA. Electronic address: andre_nussenzweig@nih.gov.
Mol Cell ; 73(6): 1267-1281.e7, 2019 03 21.
Article en En | MEDLINE | ID: mdl-30704900
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatina / Proteína BRCA1 / Ubiquitina-Proteína Ligasas / Ubiquitinación / Haploinsuficiencia / Fibroblastos / Neoplasias Límite: Animals Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatina / Proteína BRCA1 / Ubiquitina-Proteína Ligasas / Ubiquitinación / Haploinsuficiencia / Fibroblastos / Neoplasias Límite: Animals Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos