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Canine sterile steroid-responsive lymphadenitis in 49 dogs.
Ribas Latre, A; McPartland, A; Cain, D; Walker, D; Black, V; Van Den Steen, N; Warman, S; Battersby, I; Murtagh, K; Silvestrini, P; Batchelor, D; Tappin, S W.
Afiliación
  • Ribas Latre A; Dick White Referrals, Six Mile Bottom, Cambridgeshire, CB8 0UH, UK.
  • McPartland A; Davies Veterinary Specialists, Hitchin, Hertfordshire, SG5 3HR, UK.
  • Cain D; Davies Veterinary Specialists, Hitchin, Hertfordshire, SG5 3HR, UK.
  • Walker D; Anderson Moores Veterinary Specialists, Hursley, Winchester SO21 2LL, UK.
  • Black V; Langford Veterinary Service, University of Bristol, Langford, Bristol, BS40 5DU, UK.
  • Van Den Steen N; Cave Veterinary Specialists, West Buckland, Wellington TA21 9LE, UK.
  • Warman S; Langford Veterinary Service, University of Bristol, Langford, Bristol, BS40 5DU, UK.
  • Battersby I; Davies Veterinary Specialists, Hitchin, Hertfordshire, SG5 3HR, UK.
  • Murtagh K; Small Animal Teaching Hospital, University of Liverpool, Neston, Wirral CH64 7TE, UK.
  • Silvestrini P; Small Animal Teaching Hospital, University of Liverpool, Neston, Wirral CH64 7TE, UK.
  • Batchelor D; Small Animal Teaching Hospital, University of Liverpool, Neston, Wirral CH64 7TE, UK.
  • Tappin SW; Dick White Referrals, Six Mile Bottom, Cambridgeshire, CB8 0UH, UK.
J Small Anim Pract ; 60(5): 280-290, 2019 May.
Article en En | MEDLINE | ID: mdl-30684356
OBJECTIVES: To report clinical and laboratory features, treatment responses and outcome in dogs diagnosed with sterile steroid-responsive lymphadenitis in the United Kingdom. MATERIALS AND METHODS: Medical records of dogs diagnosed with sterile steroid-responsive lymphadenitis from 2009 to 2016 at six specialist referral centres were evaluated retrospectively. RESULTS: The study included 49 dogs. Springer spaniels appeared to be over-represented (16 of 49 dogs). Young dogs (median age: 3 years and 9 months) and females (31 of 49) were frequently affected. Clinical presentation was variable, with pyrexia (39 of 49), lethargy (35 of 49) and anorexia (21 of 49) the most commonly reported clinical signs. Lymph node cytology or histopathology demonstrated neutrophilic, pyogranulomatous, granulomatous or necrotising lymphadenitis without a detectable underlying cause in all cases. Because a sterile immune-mediated aetiology was suspected, all dogs received prednisolone, which was followed by rapid resolution of clinical signs and lymphadenopathy in most cases. CLINICAL SIGNIFICANCE: Sterile steroid-responsive lymphadenitis should be considered in dogs with pyrexia of unknown origin with inflammatory lymphadenopathy if no underlying cause can be found and often responds well to immunosuppressive corticosteroid therapy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de los Perros / Linfadenitis Tipo de estudio: Observational_studies Límite: Animals País/Región como asunto: Europa Idioma: En Revista: J Small Anim Pract Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de los Perros / Linfadenitis Tipo de estudio: Observational_studies Límite: Animals País/Región como asunto: Europa Idioma: En Revista: J Small Anim Pract Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido