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Mortality among United States aerospace materials manufacturing workers.
Marsh, Gary M; Buchanich, Jeanine M; Graves, Jessica; Zimmerman, Sarah; Liu, Yimeng.
Afiliación
  • Marsh GM; Department of Biostatistics, Graduate School of Public Health, Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Buchanich JM; Department of Biostatistics, Graduate School of Public Health, Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Graves J; Department of Biostatistics, Graduate School of Public Health, Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Zimmerman S; Department of Biostatistics, Graduate School of Public Health, Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Liu Y; Department of Biostatistics, Graduate School of Public Health, Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Am J Ind Med ; 62(3): 192-204, 2019 03.
Article en En | MEDLINE | ID: mdl-30676651
OBJECTIVES: To evaluate long-term mortality rates among aerospace material manufacturing workers as follow-up to an earlier observed excess of nephritis/nephrosis. METHODS: Subjects were 2020 workers ever employed in the facility during 1963-2014. Vital status through 2014 was determined for all subjects and cause of death for 99.2% of 492 deaths. We computed standard mortality ratios (SMR) and internal relative risks. RESULTS: SMRs for nephritis/nephrosis were unremarkable. We observed statistically significant elevated SMRs for kidney cancer among all workers and for the category "other lymphatic hematopoietic tissue cancer" (4/5 deaths from multiple myeloma) among long-term workers with potential plant exposure. CONCLUSIONS: We found no evidence of elevated mortality rates for nephritis/nephrosis. Study limitations precluded robust evaluation of whether the elevated rates for kidney cancer and other lymphatic hematopoietic tissue cancer were related to occupational factors at the study site. Our findings for these two cancers warrant continued mortality follow-up.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Causas de Muerte / Industria Manufacturera / Neoplasias Renales / Mieloma Múltiple / Enfermedades Profesionales Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Am J Ind Med Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Causas de Muerte / Industria Manufacturera / Neoplasias Renales / Mieloma Múltiple / Enfermedades Profesionales Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Am J Ind Med Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos