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Novel half-sandwich iridium OˆC (carbene)-Complexes: In vitro and in vivo tumor growth suppression and pro-apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes.
Xu, Zhishan; Zhang, Yujiao; Zhang, Shumiao; Jia, Xianglei; Zhong, Genshen; Yang, Yuliang; Du, Qing; Li, Juanjuan; Liu, Zhe.
Afiliación
  • Xu Z; College of Chemistry, Chemistry Engineering and Materials Science, Shandong Normal University, Jinan, 250014, China; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of
  • Zhang Y; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China.
  • Zhang S; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China.
  • Jia X; Henan Key Laboratory of Neural Regeneration, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, China.
  • Zhong G; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, 453003, China.
  • Yang Y; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China.
  • Du Q; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China.
  • Li J; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China.
  • Liu Z; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China. Elec
Cancer Lett ; 447: 75-85, 2019 04 10.
Article en En | MEDLINE | ID: mdl-30673591

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Apoptosis / Proliferación Celular / Iridio / Lisosomas / Metano / Mitocondrias Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Apoptosis / Proliferación Celular / Iridio / Lisosomas / Metano / Mitocondrias Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article Pais de publicación: Irlanda