Overexpression of miR-138-5p suppresses MnCl<sub>2</sub> -induced autophagy by targeting SIRT1 in SH-SY5Y cells.

Ma, Junxiang; Zhang, Yuanyuan; Ji, Hongyun; Chen, Li; Chen, Tian; Guo, Caixia; Zhang, Shixuan; Jia, Jiaxin; Niu, Piye

Overexpression of miR-138-5p suppresses MnCl₂ -induced autophagy by targeting SIRT1 in SH-SY5Y cells.

Ma, Junxiang; Zhang, Yuanyuan; Ji, Hongyun; Chen, Li; Chen, Tian; Guo, Caixia; Zhang, Shixuan; Jia, Jiaxin; Niu, Piye.

Afiliación

Ma J; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Zhang Y; Beijing Key Laboratory of Environmental Toxicology, School of Public Health, Capital Medical University, Beijing, China.
Ji H; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Chen L; Beijing Key Laboratory of Environmental Toxicology, School of Public Health, Capital Medical University, Beijing, China.
Chen T; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Guo C; Beijing Key Laboratory of Environmental Toxicology, School of Public Health, Capital Medical University, Beijing, China.
Zhang S; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Jia J; Beijing Key Laboratory of Environmental Toxicology, School of Public Health, Capital Medical University, Beijing, China.
Niu P; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.

Environ Toxicol ; 34(4): 539-547, 2019 Apr.

Article en En | MEDLINE | ID: mdl-30672645

Asunto(s)

Autofagia/efectos de los fármacos; Contaminantes Ambientales/toxicidad; Manganeso/toxicidad; MicroARNs/genética; Sirtuina 1/metabolismo; Regiones no Traducidas 3'/genética; Autofagia/genética; Carbazoles/farmacología; Técnicas de Cultivo de Célula; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Supervivencia Celular/genética; Humanos; Sirtuina 1/antagonistas & inhibidores

Palabras clave

MicroRNA-138-5p; SIRT1; autophagy; manganese

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / MicroARNs / Contaminantes Ambientales / Sirtuina 1 / Manganeso Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Environ Toxicol Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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