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[Analysis of 20-year survival rate and prognostic indicators of systemic lupus erythematosus].
Wang, Z R; Ren, L M; Li, R; Guan, X; Han, Q M; Liu, M L; Shao, M; Zhang, X; Chen, S; Li, Z G.
Afiliación
  • Wang ZR; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
  • Ren LM; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
  • Li R; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
  • Guan X; Department of Rheumatology and Immunology, Tong Liao City Hospital, Tongliao 028000, China.
  • Han QM; Department of Rheumatology and Immunology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China.
  • Liu ML; Department of Rheumatology and Immunology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
  • Shao M; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
  • Zhang X; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
  • Chen S; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
  • Li ZG; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing100044, China.
Zhonghua Yi Xue Za Zhi ; 99(3): 178-182, 2019 Jan 15.
Article en Zh | MEDLINE | ID: mdl-30669759
Objective: To analyze the 20-year survival rate, causes of death and predictors of systemic lupus erythematosus (SLE). Methods: A retrospective analysis was performed on 217 newly SLE patients who were diagnosed and treated by Peking University People's Hospital before June 2008. The clinical features and serologic data were studied. Survival rate of SLE patients over time, living conditions, causes of death and prognostic indicators of mortality were studied. Results: The 10-, 15-and 20-year cumulative survival rate was 90.3%,88.1%and 79.6%, respectively. Infection and lupus encephalopathy were the main causes of death. Cox regression analysis revealed that lupus nephritis, neuropsychiatric systemic lupus erythematosus and age at the diagnosis were independent risk determinants for mortality. Conclusion: Prognosis of SLE remains to be improved. Early diagnosis, control of SLE organ damage and infection prevention are critical to improve survival of SLE patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: Zh Revista: Zhonghua Yi Xue Za Zhi Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: Zh Revista: Zhonghua Yi Xue Za Zhi Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: China