Your browser doesn't support javascript.
loading
Intersections between Regulated Cell Death and Autophagy.
Napoletano, Francesco; Baron, Olga; Vandenabeele, Peter; Mollereau, Bertrand; Fanto, Manolis.
Afiliación
  • Napoletano F; Department of Life Sciences, University of Trieste, Via Weiss 2 - Pal. Q, 34128 Trieste, Italy; CIB National Laboratory, Area Science Park, Padriciano 99, 34149, Trieste, Italy.
  • Baron O; Wolfson Centre for Age-Related Disorders, King's College London, Guy's Campus, SE1 1UL, London; Department of Basic and Clinical Neuroscience, King's College London, 125 Coldharbour Lane, SE5 9NU, London, UK.
  • Vandenabeele P; Department of Biomedical Molecular Biology (DBMB), Ghent University, Ghent 9052, Belgium; VIB-UGent Center for Inflammation Research, UGent-VIB, Research Building FSVM, Technologiepark 71, 9052 Ghent, Belgium.
  • Mollereau B; Université de Lyon, ENSL, UCBL, CNRS, LBMC, UMS 3444 Biosciences Lyon Gerland, 46 Allée d'Italie, 69007, Lyon, France. Electronic address: bertrand.mollereau@ens-lyon.fr.
  • Fanto M; Department of Basic and Clinical Neuroscience, King's College London, 125 Coldharbour Lane, SE5 9NU, London, UK; Institut du Cerveau et de la Moelle épinière (ICM), 47, bd de l'hôpital, F-75013 Paris, France. Electronic address: manolis.fanto@kcl.ac.uk.
Trends Cell Biol ; 29(4): 323-338, 2019 04.
Article en En | MEDLINE | ID: mdl-30665736
In multicellular organisms, cell death is an essential aspect of life. Over the past decade, the spectrum of different forms of regulated cell death (RCD) has expanded dramatically with relevance in several pathologies such as inflammatory and neurodegenerative diseases. This has been paralleled by the growing awareness of the central importance of autophagy as a stress response that influences decisions of cell life and cell death. Here, we first introduce criteria and methodologies for correct identification of the different RCD forms. We then discuss how the autophagy machinery is directly associated with specific cell death forms and dissect the complex interactions between autophagy and apoptotic and necrotic cell death. This highlights how the balance of the relationship between other cell death pathways and autophagy presides over life and death in specific cellular contexts.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Muerte Celular Regulada Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Trends Cell Biol Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Muerte Celular Regulada Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Trends Cell Biol Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido