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Donation After Cardiac Death in Liver Transplantation: An Additional Source of Organs With Similar Results to Donation After Brain Death.
Pitarch Martínez, M; Sánchez Pérez, B; León Díaz, F J; Fernández Aguilar, J L; Pérez Daga, J A; Montiel Casado, M C; Aranda Narváez, J M; Suárez Muñoz, M Á; Santoyo Santoyo, J.
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  • Pitarch Martínez M; Department of Surgery, Obstetrics and Ginecology, Faculty of Medicine, Universidad de Málaga, Málaga, Spain; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain. Electronic address: maria.pitarchmartinez@g
  • Sánchez Pérez B; Department of Surgery, Obstetrics and Ginecology, Faculty of Medicine, Universidad de Málaga, Málaga, Spain; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • León Díaz FJ; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Fernández Aguilar JL; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Pérez Daga JA; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Montiel Casado MC; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Aranda Narváez JM; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Suárez Muñoz MÁ; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Santoyo Santoyo J; Department of Surgery, Obstetrics and Ginecology, Faculty of Medicine, Universidad de Málaga, Málaga, Spain; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.
Transplant Proc ; 51(1): 4-8, 2019.
Article en En | MEDLINE | ID: mdl-30655142
BACKGROUND: As new sources of organs are needed, liver transplantation using donors after cardiac death (DCD) is progressively increasing, but outcomes with this method are still questioned. This study was accomplished to verify that DCD outcomes are comparable to those seen in donation after brain death (DBD). METHODS: This was a prospective cohort study including 100 liver transplantation performed between 2014 and 2017, divided according to donor type in 75 DBD and 25 DCD. RESULTS: DCD donors were younger (mean age: DCD 56 years, DBD 59 years; P = .009). Mean Modified End-stage Liver Disease (MELD) score was lower for DCD (DCD 16, DBD 19; P < .001). No differences were found regarding ischemia times and development of postreperfusion syndrome or coagulopathy. Primary graft dysfunction was more frequent in DCD (60%, DCD 29.3%; P = .006). Rates of primary graft nonfunction (DCD 0%, DBD 1.3%; P = .562) and acute rejection (DCD 20%, DBD 16.4%; P = .685) were similar. Acute kidney injury occurred more often in DBD (DCD 32%, DBD 12%; P = .051). Length of stay was comparable. Rates of biliary complications (DCD 20%, DBD 26.7%; P = .505) were similar, unlike ischemic cholangiopathy (DCD 12%, DBD 1.3%; P = .018). Retransplantation rates were also similar (DCD 8%, DBD 4%; P = .427) as was survival rate after 3 years (DCD 84%, DBD 86.7%; P = .739). CONCLUSION: DCD represents an additional graft source with results that are encouraging and may be comparable to DBD with a careful donor and recipient selection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Hígado / Muerte / Supervivencia de Injerto Tipo de estudio: Observational_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transplant Proc Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Hígado / Muerte / Supervivencia de Injerto Tipo de estudio: Observational_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transplant Proc Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos