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Case Report: Hemophagocytic Lymphohistiocytosis Caused by Disseminated Histoplasmosis in a Venezuelan Patient with HIV and Epstein-Barr Virus Reactivation Who Traveled to Japan.
Tsuboi, Motoyuki; Nishijima, Takeshi; Nagi, Minoru; Miyazaki, Yoshitsugu; Teruya, Katsuji; Kikuchi, Yoshimi; Gatanaga, Hiroyuki; Oka, Shinichi.
Afiliación
  • Tsuboi M; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Nishijima T; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Nagi M; Department of Mycology, National Institute of Infectious Diseases, Tokyo, Japan.
  • Miyazaki Y; Department of Mycology, National Institute of Infectious Diseases, Tokyo, Japan.
  • Teruya K; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Kikuchi Y; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Gatanaga H; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Oka S; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Am J Trop Med Hyg ; 100(2): 365-367, 2019 02.
Article en En | MEDLINE | ID: mdl-30652668
We describe a Venezuelan visitor to Japan who was diagnosed with hemophagocytic lymphohistiocytosis (HLH). The patient was also diagnosed with human immunodeficiency virus (HIV) and Epstein-Barr virus infection by the Western blot and polymerase chain reaction (PCR) tests, respectively. The cause of HLH was considered to be these two infections at first; however, the patient did not recover with antiretroviral/anti-herpes virus therapy. Thereafter, diagnosis of disseminated histoplasmosis was confirmed with an antigen detection test, culture, and PCR test of blood, urine, and bone marrow, and the patient improved gradually after the initiation of liposomal amphotericin B. This case highlights the importance of ruling out endemic mycosis as a cause of HLH even if other probable causes exist in patients from endemic areas.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Infecciones por Virus de Epstein-Barr / Linfohistiocitosis Hemofagocítica / Histoplasmosis Límite: Female / Humans / Middle aged País/Región como asunto: America do sul / Asia / Venezuela Idioma: En Revista: Am J Trop Med Hyg Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Infecciones por Virus de Epstein-Barr / Linfohistiocitosis Hemofagocítica / Histoplasmosis Límite: Female / Humans / Middle aged País/Región como asunto: America do sul / Asia / Venezuela Idioma: En Revista: Am J Trop Med Hyg Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos