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Multiplex assay for multiomics advances in personalized-precision medicine.
Popa, Maria-Linda; Albulescu, Radu; Neagu, Monica; Hinescu, Mihail Eugen; Tanase, Cristiana.
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  • Popa ML; a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
  • Albulescu R; b Cellular and Molecular Biology and Histology Department , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.
  • Neagu M; a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
  • Hinescu ME; c Pharmaceutical Biotechnology Department , National Institute for Chemical-Pharmaceutical R&D , Bucharest , Romania.
  • Tanase C; a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
J Immunoassay Immunochem ; 40(1): 3-25, 2019.
Article en En | MEDLINE | ID: mdl-30632882
Building the future of precision medicine is the main focus in cancer domain. Clinical trials are moving toward an array of studies that are more adapted to precision medicine. In this domain, there is an enhanced need for biomarkers, monitoring devices, and data-analysis methods. Omics profiling using whole genome, epigenome, transcriptome, proteome, and metabolome can offer detailed information of the human body in an integrative manner. Omes profiles reflect more accurately real-time physiological status. Personalized omics analyses both disease as a whole and the main disease processes, for a better understanding of the individualized health. Through this, multi-omic approaches for health monitoring, preventative medicine, and personalized treatment can be targeted simultaneously and can lead clinicians to have a comprehensive view on the diseasome.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteoma / Metaboloma / Medicina de Precisión / Epigenómica / Transcriptoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Immunoassay Immunochem Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteoma / Metaboloma / Medicina de Precisión / Epigenómica / Transcriptoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Immunoassay Immunochem Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Reino Unido