Your browser doesn't support javascript.
loading
Effect of an Energy-Restricted, Nutritionally Complete, Higher Protein Meal Plan on Body Composition and Mobility in Older Adults With Obesity: A Randomized Controlled Trial.
Beavers, Kristen M; Nesbit, Beverly A; Kiel, Jessica R; Sheedy, Jessica L; Arterburn, Linda M; Collins, Amy E; Ford, Sherri A; Henderson, Rebecca M; Coleman, Christopher D; Beavers, Daniel P.
Afiliación
  • Beavers KM; Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
  • Nesbit BA; Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
  • Kiel JR; Department of Scientific and Clinical Affairs, Medifast, Inc., Baltimore, Maryland.
  • Sheedy JL; Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
  • Arterburn LM; Department of Scientific and Clinical Affairs, Medifast, Inc., Baltimore, Maryland.
  • Collins AE; Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
  • Ford SA; Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
  • Henderson RM; Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Winston-Salem, North Carolina.
  • Coleman CD; Department of Scientific and Clinical Affairs, Medifast, Inc., Baltimore, Maryland.
  • Beavers DP; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
J Gerontol A Biol Sci Med Sci ; 74(6): 929-935, 2019 05 16.
Article en En | MEDLINE | ID: mdl-30629126
BACKGROUND: Increasing protein content of the diet might be an effective strategy to preserve muscle mass in older adults undergoing caloric restriction, thereby preserving muscle function. METHODS: Ninety-six older adults (70.3 ± 3.7 years, 74% women, 27% African American) with obesity (35.4 ± 3.3 kg/m2; 47% total body fat) were randomized to a 6-month higher protein (providing 1.2-1.5 g/kg/d) weight loss (WL) program, utilizing the Medifast 4&2&1 Plan, or to weight stability (WS). Dual-energy x-ray absorptiometry-acquired total body mass and composition, and fast gait speed over 400 m was assessed at baseline, 3, and 6 months. RESULTS: At baseline, dual-energy x-ray absorptiometry-acquired total body, fat, and lean masses were 95.9 ± 14.6, 44.6 ± 7.6, and 48.7 ± 9.5 kg, respectively, and 400-m gait speed was 1.17 ± 0.20 m/s. Total body mass was significantly reduced in the WL group (-8.17 [-9.56, -6.77] kg) compared with the WS group (-1.16 [-2.59, 0.27] kg), with 87% of total mass lost as fat (WL: -7.1 [-8.1, -6.1] kg; -15.9% change from baseline). A differential treatment effect was not observed for change in lean mass (WL: -0.81 [-1.40, -0.23] kg vs WS: -0.24 [-0.85, 0.36] kg). Four-hundred-meter gait speed was also unchanged from baseline although trends suggest slightly increased gait speed in the WL group [0.01 (-0.02, 0.04) m/s] compared with the WS group [-0.02 (-0.05, 0.01) m/s]. CONCLUSION: Intentional weight loss using a high-protein diet is effective in producing significant total body mass and fat mass loss, while helping preserve lean body mass and mobility, in relatively high-functioning older adults with obesity.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Composición Corporal / Proteínas en la Dieta / Restricción Calórica / Obesidad Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male Idioma: En Revista: J Gerontol A Biol Sci Med Sci Asunto de la revista: GERIATRIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Composición Corporal / Proteínas en la Dieta / Restricción Calórica / Obesidad Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male Idioma: En Revista: J Gerontol A Biol Sci Med Sci Asunto de la revista: GERIATRIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos