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The (R)-enantiomer of the 6-chromanol derivate SUL-121 improves renal graft perfusion via antagonism of the α1-adrenoceptor.
Nakladal, D; Buikema, H; Romero, A Reyes; Lambooy, S P H; Bouma, J; Krenning, G; Vogelaar, P; van der Graaf, A C; Groves, M R; Kyselovic, J; Henning, R H; Deelman, L E.
Afiliación
  • Nakladal D; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.
  • Buikema H; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32, Bratislava, Slovakia.
  • Romero AR; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.
  • Lambooy SPH; Department of Drug Design, School of Pharmacy, University of Groningen, Antonius Deusinglaan 1 Postbus 196, 9700 AD, Groningen, The Netherlands.
  • Bouma J; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.
  • Krenning G; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.
  • Vogelaar P; Cardiovascular Regenerative Medicine, Dept. Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • van der Graaf AC; Sulfateq B.V., Admiraal de Ruyterlaan 5, 9726GN, Groningen, The Netherlands.
  • Groves MR; Sulfateq B.V., Admiraal de Ruyterlaan 5, 9726GN, Groningen, The Netherlands.
  • Kyselovic J; Sulfateq B.V., Admiraal de Ruyterlaan 5, 9726GN, Groningen, The Netherlands.
  • Henning RH; Department of Drug Design, School of Pharmacy, University of Groningen, Antonius Deusinglaan 1 Postbus 196, 9700 AD, Groningen, The Netherlands.
  • Deelman LE; 5th Department of Internal Medicine, Faculty of Medicine, University Hospital, Commenius University, Bratislava, Slovak Republic.
Sci Rep ; 9(1): 13, 2019 01 09.
Article en En | MEDLINE | ID: mdl-30626882
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperazinas / Vasoconstricción / Cromanos / Receptores Adrenérgicos alfa 1 / Antagonistas de Receptores Adrenérgicos alfa 1 / Riñón Límite: Animals Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperazinas / Vasoconstricción / Cromanos / Receptores Adrenérgicos alfa 1 / Antagonistas de Receptores Adrenérgicos alfa 1 / Riñón Límite: Animals Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido