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Chemical constituents isolated from stems of Schisandra chinensis and their antifeedant activity against Tribolium castaneum.
Guo, Shan-Shan; Pang, Xue; Wang, Yang; Geng, Zhu-Feng; Cao, Ju-Qin; Liang, Jun-Yu; Deng, Zhi-Wei; Du, Shu-Shan.
Afiliación
  • Guo SS; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China.
  • Pang X; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China.
  • Wang Y; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China.
  • Geng ZF; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China.
  • Cao JQ; Analytical and Testing Center, Beijing Normal University, Beijing, China.
  • Liang JY; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China.
  • Deng ZW; Medical Chemistry Department, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
  • Du SS; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China.
Nat Prod Res ; 34(18): 2595-2601, 2020 Sep.
Article en En | MEDLINE | ID: mdl-30623674
One new sesquiterpene (α-iso-cubebenol acetate, 8), together with 9 known compounds (1-7, 9, 10) were isolated from the stems of Schisandra chinensis (Turcz.) Baill. by repeated silica gel column chromatography. Based on the results of MS, NMR spectra and comparing with literature data, the six dibenzocyclooctadiene lignans were identified as schizandrin A to C (1-3), schizandrin (4), schisantherin A (5) and gomisin J (6), the two sesquiterpenes were identified as α-iso-cubebenol (7) and α-iso-cubebenol acetate (8), while the two triterpenic acids were identified as ganwuweizic acid (9) and kadsuric acid (10). The antifeedant activity of the 10 compounds against Tribolium castaneum adults was tested. Gomisin J (6) exhibited activity at 1500 ppm concentration with 40.3% antifeeding index percentages. As for the dibenzocyclooctene lignans (compounds 1-3, 6), the number of methylenedioxies and the position of hydroxyl groups were the main factors to affect their antifeedant activities.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tribolium / Lignanos / Tallos de la Planta / Schisandra / Ciclooctanos / Conducta Alimentaria Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tribolium / Lignanos / Tallos de la Planta / Schisandra / Ciclooctanos / Conducta Alimentaria Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido