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Risk factors associated with the detection and missed diagnosis of colorectal flat adenoma: a Chinese multicenter observational study.
Xiang, Li; Zhan, Qiang; Wang, Xian-Fei; Zhao, Xin-Hua; Zhou, Yong-Bai; An, Sheng-Li; Han, Ze-Long; Wang, Ya-Dong; Xu, Yang-Zhi; Li, Ai-Min; Zhang, Ya-Li; Liu, Si-De.
Afiliación
  • Xiang L; a Department of Gastroenterology , Nanfang Hospital, Southern Medical University , Guangzhou , China.
  • Zhan Q; b Department of Gastroenterology , Longgang district People's Hospital , Shenzhen , Guangdong Province , China.
  • Wang XF; c Department of Gastroenterology , Wuxi City People's Hospital Affiliated to Nanjing Medical University , Wuxi , China.
  • Zhao XH; d Department of Gastroenterology , Affiliated Hospital of North Sichuan Medical College , Nanchong , China.
  • Zhou YB; e Department of Gastroenterology , Mianyang Central Hospital , Mianyang , China.
  • An SL; f Department of Gastroenterology , Longgang Central Hospital , Shenzhen , China.
  • Han ZL; g Department of Biostatistics , School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou , China.
  • Wang YD; a Department of Gastroenterology , Nanfang Hospital, Southern Medical University , Guangzhou , China.
  • Xu YZ; a Department of Gastroenterology , Nanfang Hospital, Southern Medical University , Guangzhou , China.
  • Li AM; a Department of Gastroenterology , Nanfang Hospital, Southern Medical University , Guangzhou , China.
  • Zhang YL; a Department of Gastroenterology , Nanfang Hospital, Southern Medical University , Guangzhou , China.
  • Liu SD; a Department of Gastroenterology , Nanfang Hospital, Southern Medical University , Guangzhou , China.
Scand J Gastroenterol ; 53(12): 1519-1525, 2018 Dec.
Article en En | MEDLINE | ID: mdl-30621477
OBJECTIVES: Flat colorectal adenomas have a high risk of malignancy; however, their detection is often difficult due to their flat morphology. In this retrospective, large-scale study, we investigated the prevalence and characteristics of flat adenomas in a population in China. METHODS: We analyzed the data collected for 16951 consecutive patients who underwent colonoscopy at four participating hospitals between September 2013 and September 2015. All colonoscopies were performed without magnification. RESULTS: Among the 1,6951 patients, 2938 (17.3%) had adenoma and 796 (4.7%) had flat adenomas. The detection of flat adenoma showed a weak correlation with the detection of adenoma (r = 0.666). Multivariable logistic regression analysis revealed the following independent factors influencing the detection of flat adenomas: patient-related factors of age, presence of warning symptoms, history of adenomas and bowel preparation as well as endoscopist-related factors of endoscopist's level of proficiency, number of colonoscopy operators and withdrawal time. CONCLUSIONS: The prevalence of flat adenomas in our study on Chinese patients was consistent with that reported from other countries. Factors conducive to the detection of flat adenomas were patient age of > 60 years, warning symptoms, history of adenoma, good bowel preparation, experienced endoscopist, single-operator colonoscopy and colonoscopy withdrawal time of >6 min.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Adenoma / Colonoscopía / Errores Diagnósticos Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Scand J Gastroenterol Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Adenoma / Colonoscopía / Errores Diagnósticos Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Scand J Gastroenterol Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido