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A modified physiologic test for bronchopulmonary dysplasia: a clinical tool for weaning from CPAP and/or oxygen-therapy the premature babies?
Vento, Giovanni; Vendettuoli, Valentina; Aurilia, Claudia; Tana, Milena; Tirone, Chiara; Lio, Alessandra; Matassa, Piero Giuseppe; Priolo, Francesca; Catenazzi, Piero; Corsello, Mirta; Zecca, Enrico; Mosca, Fabio.
Afiliación
  • Vento G; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. giovanni.vento@unicatt.it.
  • Vendettuoli V; Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168, Rome, Italy. giovanni.vento@unicatt.it.
  • Aurilia C; Neonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
  • Tana M; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Tirone C; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Lio A; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Matassa PG; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Priolo F; Neonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
  • Catenazzi P; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Corsello M; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Zecca E; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Mosca F; Division of Neonatology, Department of Pediatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Ital J Pediatr ; 45(1): 2, 2019 Jan 04.
Article en En | MEDLINE | ID: mdl-30609929
BACKGROUND: A physiologic test for estimating BPD rate has been developed by Walsh and collaborators. Actually there are not standard criteria for weaning from CPAP and/or oxygen therapy the premature babies. Aim of this study was to verify if a physiologic test, modified respect to that developed by Walsh and collaborators for estimating BPD rate, can be used as a clinical tool for weaning the premature babies from CPAP and/or oxygen therapy. METHODS: Neonates with BW 500-1250 g and GA ≤ 32 weeks, receiving FiO2 ≤ 0.30 by hood or CPAP, were prospectively studied at 28 days of life and at 36 weeks of postmestrual age. The test was performed in 3 steps: baseline, challenge (FiO2 and CPAP reduction to room air) and post test (room air). Monitoring of transcutaneous CO2 was added to SpO2 and the newborns passing the test were left in room air. RESULTS: Six of 23 tested babies (26%) passed the challenge at 28 days of life, 4 of 10 tested babies (40%) passed the challenge at 36 weeks. Median values of SpO2 were significantly higher in the neonates passing the test, respect to the failing patients. At the same time median values of TcPCO2 were significantly higher in the latter babies. CONCLUSION: TcPCO2 monitoring appeared to be a new useful parameter for failure prediction of weaning. The test represented a clinical guide because the newborns passing it were left in room air.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monitoreo de Gas Sanguíneo Transcutáneo / Desconexión del Ventilador Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Ital J Pediatr Asunto de la revista: PEDIATRIA Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monitoreo de Gas Sanguíneo Transcutáneo / Desconexión del Ventilador Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Ital J Pediatr Asunto de la revista: PEDIATRIA Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido