TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.

Zhang, Xiupeng; Han, Shuai; Zhou, Haijing; Cai, Lin; Li, Jingduo; Liu, Nan; Liu, Yang; Wang, Liang; Fan, Chuifeng; Li, Ailin; Miao, Yuan

Zhang, Xiupeng; Han, Shuai; Zhou, Haijing; Cai, Lin; Li, Jingduo; Liu, Nan; Liu, Yang; Wang, Liang; Fan, Chuifeng; Li, Ailin; Miao, Yuan.

Afiliación

Zhang X; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Han S; Department of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Zhou H; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Cai L; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Li J; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Liu N; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Liu Y; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Wang L; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Fan C; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.
Li A; Department of Radiotherapy, The First Affiliated Hospital of China Medical University, Shenyang, China.
Miao Y; Department of Pathology, College of Basic Medical Science and the First Affiliated Hospital of China Medical University, Shenyang, China.

Mol Carcinog ; 58(5): 767-776, 2019 05.

Article en En | MEDLINE | ID: mdl-30604908

Asunto(s)

Biomarcadores de Tumor/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/patología; Regulación Neoplásica de la Expresión Génica; Neoplasias Pulmonares/patología; Proteínas de Transporte de Membrana/metabolismo; Proteínas Quinasas S6 Ribosómicas 90-kDa/metabolismo; Adenocarcinoma/genética; Adenocarcinoma/metabolismo; Adenocarcinoma/secundario; Adulto; Anciano; Apoptosis; Biomarcadores de Tumor/genética; Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/secundario; Estudios de Casos y Controles; Proliferación Celular; Femenino; Estudios de Seguimiento; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Metástasis Linfática; Masculino; Proteínas de Transporte de Membrana/genética; Persona de Mediana Edad; Proteínas del Complejo de Importación de Proteínas Precursoras Mitocondriales; Proteína Quinasa 3 Activada por Mitógenos/genética; Proteína Quinasa 3 Activada por Mitógenos/metabolismo; Invasividad Neoplásica; Fosforilación; Pronóstico; Proteínas Quinasas S6 Ribosómicas 90-kDa/genética; Transducción de Señal; Tasa de Supervivencia; Células Tumorales Cultivadas

Palabras clave

TIMM50; invasion; non-small cell lung cancer; prognosis; proliferation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Carcinoma de Pulmón de Células no Pequeñas / Proteínas Quinasas S6 Ribosómicas 90-kDa / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Mol Carcinog Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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