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Akt2 mediates glucocorticoid resistance in lymphoid malignancies through FoxO3a/Bim axis and serves as a direct target for resistance reversal.
Xie, Mixue; Yang, Apeng; Ma, Jiexian; Wu, Min; Xu, Hongyue; Wu, Kefei; Jin, Youxin; Xie, Yanhui.
Afiliación
  • Xie M; Senior Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.
  • Yang A; Department of Hematology & Rheumatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China.
  • Ma J; Department of Hematology & Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, China.
  • Wu M; Department of Hematology & Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, China.
  • Xu H; Department of Hematology & Oncology, The Second People's Hospital of Liaocheng, Liaocheng, 252600, China.
  • Wu K; Department of Hematology & Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, China.
  • Jin Y; The School of Life Sciences, Shanghai University, Shanghai, 200444, China. xyh@medmail.com.cn.
  • Xie Y; Department of Hematology & Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, China. yxjin@sibs.ac.cn.
Cell Death Dis ; 9(10): 1013, 2019 01 01.
Article en En | MEDLINE | ID: mdl-30598523
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia de Células T / Transducción de Señal / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-akt / Proteína 11 Similar a Bcl2 / Proteína Forkhead Box O3 / Glucocorticoides Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia de Células T / Transducción de Señal / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-akt / Proteína 11 Similar a Bcl2 / Proteína Forkhead Box O3 / Glucocorticoides Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido