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Ten-year single-centre experience in fertility preservation of 459 patients suffering from acute leukaemia.
Noetzli, Jasmine; Voruz, Sophie; Wunder, Dorothea; Primi, Marie-Pierre; Spertini, Olivier; Blum, Sabine.
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  • Noetzli J; Service and Central Laboratory of Haematology, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
  • Voruz S; Service and Central Laboratory of Haematology, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
  • Wunder D; UMR, Gynaecology and Obstetrics, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
  • Primi MP; Andrology Laboratory, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
  • Spertini O; Service and Central Laboratory of Haematology, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
  • Blum S; Service and Central Laboratory of Haematology, University Hospital Lausanne (CHUV), Lausanne, Switzerland.
Br J Haematol ; 184(6): 969-973, 2019 03.
Article en En | MEDLINE | ID: mdl-30592029
Acute leukaemia is a life-threatening disease that needs treatment without delay. Fertility preservation is recommended, but often not possible because of the necessity to start treatment as soon as possible. The present study is a retrospective single-centre analysis of 459 patients diagnosed with acute leukaemia between 2002 and 2012. Sperm or oocyte preservation was successfully performed in only 29 (6%) patients. Of the 150 children, no paediatric patient sample was taken. The collected samples enabled the conception of 2 children by in vitro fertilisation; in addition, 3 spontaneous, non-assisted births in partners of male patients were observed. Fertility preservation is important but difficult to accomplish in patients with acute leukaemia; more efforts are clearly needed to preserve fertility in long-term survivors of acute leukaemia.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Preservación de la Fertilidad Tipo de estudio: Observational_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Br J Haematol Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Preservación de la Fertilidad Tipo de estudio: Observational_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Br J Haematol Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido