Elevated Wall Tension Leads to Reduced miR-133a in the Thoracic Aorta by Exosome Release.

Akerman, Adam W; Blanding, Walker M; Stroud, Robert E; Nadeau, Elizabeth K; Mukherjee, Rupak; Ruddy, Jean Marie; Zile, Michael R; Ikonomidis, John S; Jones, Jeffrey A

Akerman, Adam W; Blanding, Walker M; Stroud, Robert E; Nadeau, Elizabeth K; Mukherjee, Rupak; Ruddy, Jean Marie; Zile, Michael R; Ikonomidis, John S; Jones, Jeffrey A.

Afiliación

Akerman AW; 1 Division of Cardiothoracic Surgery Department of Surgery Medical University of South Carolina Charleston SC.
Blanding WM; 4 Cardiothoracic Surgery Research University of North Carolina at Chapel Hill NC.
Stroud RE; 1 Division of Cardiothoracic Surgery Department of Surgery Medical University of South Carolina Charleston SC.
Nadeau EK; 1 Division of Cardiothoracic Surgery Department of Surgery Medical University of South Carolina Charleston SC.
Mukherjee R; 1 Division of Cardiothoracic Surgery Department of Surgery Medical University of South Carolina Charleston SC.
Ruddy JM; 1 Division of Cardiothoracic Surgery Department of Surgery Medical University of South Carolina Charleston SC.
Zile MR; 2 Research Service Ralph H. Johnson Veterans Affairs Medical Center Charleston SC.
Ikonomidis JS; 3 Division of Vascular Surgery Medical University of South Carolina Charleston SC.
Jones JA; 1 Division of Cardiothoracic Surgery Department of Surgery Medical University of South Carolina Charleston SC.

J Am Heart Assoc ; 8(1): e010332, 2019 01 08.

Article en En | MEDLINE | ID: mdl-30572760

Asunto(s)

Aorta Torácica/metabolismo; Aneurisma de la Aorta Torácica/genética; Exoma/genética; Regulación de la Expresión Génica; MicroARNs/genética; Animales; Aorta Torácica/diagnóstico por imagen; Aneurisma de la Aorta Torácica/metabolismo; Aneurisma de la Aorta Torácica/patología; Células Cultivadas; Modelos Animales de Enfermedad; Femenino; Fibroblastos/metabolismo; Fibroblastos/patología; Humanos; Immunoblotting; Masculino; Ratones; Ratones Endogámicos C57BL; MicroARNs/biosíntesis; ARN Mensajero/genética

Palabras clave

exosome secretion; fibroblasts; hypertension; microRNA; thoracic aorta; vascular biology; wall tension

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aorta Torácica / Regulación de la Expresión Génica / Aneurisma de la Aorta Torácica / MicroARNs / Exoma Límite: Animals / Female / Humans / Male Idioma: En Revista: J Am Heart Assoc Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google