Dual-Specificity Phosphatase CDC25B Was Inhibited by Natural Product HB-21 Through Covalently Binding to the Active Site.

Zhang, Shoude; Jia, Qiangqiang; Gao, Qiang; Fan, Xueru; Weng, Yuxin; Su, Zhanhai

Zhang, Shoude; Jia, Qiangqiang; Gao, Qiang; Fan, Xueru; Weng, Yuxin; Su, Zhanhai.

Afiliación

Zhang S; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, China.
Jia Q; Department of Pharmacy, Medical College of Qinghai University, Xining, China.
Gao Q; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, China.
Fan X; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, China.
Weng Y; Department of Pharmacy, Medical College of Qinghai University, Xining, China.
Su Z; Department of Pharmacy, Medical College of Qinghai University, Xining, China.

Front Chem ; 6: 531, 2018.

Article en En | MEDLINE | ID: mdl-30555816

Palabras clave

Cdc25B inhibitor; anticancer; cell cycle progression; covalent binding to protein; sesquiterpene lactone

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Chem Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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