4HNE, 4-Hydroxynonenal; 8-OHdG, 8-Hydroxydeoxyguanosine; ALOX12, Arachidonate 12-lipoxygenase; AOD, Antioxidative defense; CAT, Catalase; DNL, de novo lipogenesis; FA, Fatty acid; GPx, Glutathione peroxidase; GSH, Reduced glutathione; GSSG, Oxidized glutathione; H2O2, Hydrogen peroxide; HFD, High-fat diet; HIF, Hypoxia-inducible factor; Hepatic fatty acid metabolism; IL, Interleukin; IR, Ischemia/reperfusion; IRI, Ischemia/reperfusion injury; LPO, Lipid peroxidation; Lipid peroxidation; MDA, Malondialdehyde; NFκB, Nuclear factor kappa B; O2, Oxygen; O2­, Superoxide anion; OH⁎, Hydroxyl radical; Oxidative stress; ROS, Reactive oxygen species; Reactive oxygen species; Steatosis; TBARS, Thiobarbituric acid reactive substances; TG, Triglyceride; TNF, Tumor necrosis factor; UCP2, Uncoupling protein-2; cAMP, Cyclic adenosine monophosphate