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The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy.
Liu, Suhu; Marneth, Anna E; Alexe, Gabriela; Walker, Sarah R; Gandler, Helen I; Ye, Darwin Q; Labella, Katherine; Mathur, Radhika; Toniolo, Patricia A; Tillgren, Michelle; Gokhale, Prafulla C; Barbie, David; Mullally, Ann; Stegmaier, Kimberly; Frank, David A.
Afiliación
  • Liu S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Marneth AE; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Alexe G; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Walker SR; Department of Pediatric Oncology and.
  • Gandler HI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Ye DQ; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Labella K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Mathur R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Toniolo PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Tillgren M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Gokhale PC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Barbie D; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, and.
  • Mullally A; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, and.
  • Stegmaier K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Frank DA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Blood Adv ; 2(23): 3428-3442, 2018 12 11.
Article en En | MEDLINE | ID: mdl-30504235

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteínas Proto-Oncogénicas c-myc / Proteínas Serina-Treonina Quinasas / Quinasa I-kappa B / Proteína 1 de Unión a la Caja Y Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Adv Año: 2018 Tipo del documento: Article País de afiliación: Marruecos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteínas Proto-Oncogénicas c-myc / Proteínas Serina-Treonina Quinasas / Quinasa I-kappa B / Proteína 1 de Unión a la Caja Y Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Adv Año: 2018 Tipo del documento: Article País de afiliación: Marruecos Pais de publicación: Estados Unidos