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Closing gastroschisis: The good, the bad, and the not-so ugly.
Perrone, Erin E; Olson, Jacob; Golden, Jamie M; Besner, Gail E; Gayer, Christopher P; Islam, Saleem; Gollin, Gerald.
Afiliación
  • Perrone EE; University of Michigan, Michigan Medicine, Department of Surgery, Section of Pediatric Surgery, C.S. Mott Children's Hospital, Ann Arbor, MI; University of Michigan, Fetal Diagnosis and Treatment Center. Electronic address: eperrone@med.umich.edu.
  • Olson J; Loma Linda University Children's Hospital, Loma Linda, CA; Nationwide Children's Hospital, Columbus, OH 43205. Electronic address: JKOlson@llu.edu.
  • Golden JM; Children's Hospital of Los Angeles, Los Angeles, CA. Electronic address: Jamie.m.golden@gmail.com.
  • Besner GE; Nationwide Children's Hospital, Columbus, OH 43205. Electronic address: gail.besner@nationwidechildrens.org.
  • Gayer CP; Children's Hospital of Los Angeles, Los Angeles, CA. Electronic address: cgayer@chla.usc.edu.
  • Islam S; University of Florida, Gainesville, FL. Electronic address: saleem.islam@surgery.ufl.edu.
  • Gollin G; Rady Children's Hospital, San Diego, CA. Electronic address: ggollin@rchsd.org.
J Pediatr Surg ; 54(1): 60-64, 2019 Jan.
Article en En | MEDLINE | ID: mdl-30482541
PURPOSE: The diagnosis of "closing" or "closed gastroschisis" is made when bowel is incarcerated within a closed or nearly closed ring of fascia, usually with associated bowel atresia. It has been described as having a high morbidity and mortality. METHODS: A retrospective review of closing gastroschisis cases (n = 53) at six children's hospitals between 2000 and 2016 was completed after IRB approval. RESULTS: A new classification system for this disease was developed to represent the spectrum of the disease: Type A (15%): ischemic bowel that is constricted at the ring but without atresia; Type B (51%): intestinal atresia with a mass of ischemic, but viable, external bowel (owing to constriction at the ring); Type C (26%): closing ring with nonviable external bowel +/- atresia; and Type D (8%): completely closed defect with either a nubbin of exposed tissue or no external bowel. Overall, 87% of infants survived, and long-term data are provided for each type. CONCLUSIONS: This new classification system better captures the spectrum of disease and describes the expected long-term results for counseling. Unless the external bowel in a closing gastroschisis is clearly necrotic, it should be reduced and evaluated later. Survival was found to be much better than previously reported. TYPE OF STUDY: Retrospective case series with no comparison group. LEVEL OF EVIDENCE: Level IV.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gastrosquisis Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Newborn Idioma: En Revista: J Pediatr Surg Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gastrosquisis Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Newborn Idioma: En Revista: J Pediatr Surg Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos