Animal Models for Influenza A Virus Infection Incorporating the Involvement of Innate Host Defenses: Enhanced Translational Value of the Porcine Model.

Starbæk, Sofie M R; Brogaard, Louise; Dawson, Harry D; Smith, Allen D; Heegaard, Peter M H; Larsen, Lars E; Jungersen, Gregers; Skovgaard, Kerstin

Starbæk, Sofie M R; Brogaard, Louise; Dawson, Harry D; Smith, Allen D; Heegaard, Peter M H; Larsen, Lars E; Jungersen, Gregers; Skovgaard, Kerstin.

Afiliación

Starbæk SMR; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Brogaard L; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Dawson HD; Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland.
Smith AD; Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland.
Heegaard PMH; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Larsen LE; National Veterinary Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Jungersen G; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Skovgaard K; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.

ILAR J ; 59(3): 323-337, 2018 12 31.

Article en En | MEDLINE | ID: mdl-30476076

Asunto(s)

Virus de la Influenza A/patogenicidad; Gripe Humana/virología; Animales; Modelos Animales de Enfermedad; Humanos; Inmunidad Innata/genética; Inmunidad Innata/fisiología; Inflamación/metabolismo; Gripe Humana/genética; MicroARNs/metabolismo; Infecciones por Orthomyxoviridae/inmunología; Infecciones por Orthomyxoviridae/virología; Porcinos

Palabras clave

animal model; antiviral; inflammation; influenza A virus; innate immune response; microRNA; translational value; validity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus de la Influenza A / Gripe Humana Límite: Animals / Humans Idioma: En Revista: ILAR J Asunto de la revista: MEDICINA VETERINARIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2018 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido

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